概述

  • 产品名称
  • 描述
    兔多克隆抗体to RPT2
  • 特异性
    ab22679 reacts with 19S regulator ATPase subunit Rpt2p (Yta5).
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Saccharomyces cerevisiae
  • 免疫原

    Recombinant (His-tagged) fusion protein: MGQGVSSGQD KKKKKGSNQK PKYEPPVQSK FGRKKRKGGP ATAEKLPNIY PSTRCKLKLL RMERIKDHLL LEEEFVSNSE ILKPFEKKQE EEKKQLEEIR, corresponding to N terminal amino acids 1-100 of S. cerevisiae RPT2.

性能

应用

Our Abpromise guarantee covers the use of ab22679 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明
    WB: 1/10000 - 1/50000. Detects a band of approximately 48 kDa.
    Notes: Dilute to working strength with phosphate buffered saline pH 7.2-7.4 and 1% normal goat serum (if a goat anti-rabbit IgG linker antibody is to be used).

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性
      In the yeast, S. cerevisiae, 12 different members of a novel gene family of putative ATPases have been identified and characterised. Due to their relationship with TBP-1, a human immunodeficiency tat-binding protein, they have been designated the YTA family (yeast tat-binding analogues). The most outstanding feature of the YTA proteins and their relatives is that they share a region of high similarity which extends to some 300 amino acids in length. The amino acid sequences preceding the region of high similarity are less well conserved but do contain similar structural domains, i.e. coil-coil propensities, leucine zipper-like structures. However, despite the highly conserved structural features among the YTA family, diverse functions have been assigned to the various family members. The putative gene products of YTA1, YTA2, YTA3 and YTA5 are all closely related to proteins known to be constituents of the human 26S proteasome. RPT2 (YTA5), of all members of the YTA family, shows the highest similarity with subunit 4 of the human 26S proteasome, and is presumed to be the true yeast homologue.
    • 细胞定位
      Cytoplasmic and Nuclear
    • 数据库链接
      • 别名
        • 26S protease regulatory subunit 4 homolog antibody
        • P26s4 antibody
        • TAT binding homolog 5 antibody
        • YHS4 antibody
        • YTA5 antibody
        see all

      图片

      实验方案

      文献

      ab22679 has not yet been referenced specifically in any publications.

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      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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