概述

  • 产品名称
  • 描述
    兔多克隆抗体to RPS19
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 104-133 of Human RPS19 (NP_001013.1).

  • 阳性对照
    • 293 cell line lysates.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    ab123290 is purified through a protein A column, followed by peptide affinity purification.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab123290 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 16 kDa.

靶标

  • 功能
    Required for pre-rRNA processing and maturation of 40S ribosomal subunits.
  • 组织特异性
    Higher level expression is seen in the colon carcinoma tissue than normal colon tissue.
  • 疾病相关
    Defects in RPS19 are the cause of Diamond-Blackfan anemia type 1 (DBA1) [MIM:105650]. DBA1 is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies.
  • 序列相似性
    Belongs to the ribosomal protein S19e family.
  • 细胞定位
    Nucleus. Located more specifically in the nucleoli.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 40S ribosomal protein S19 antibody
    • DBA antibody
    • DBA1 antibody
    • HGNC:10402 antibody
    • Ribosomal protein S19 antibody
    • rps19 antibody
    • RS19_HUMAN antibody
    • S19 antibody
    see all

Anti-RPS19 antibody 图像

  • Anti-RPS19 antibody (ab123290) at 1/100 dilution + 293 cell line lysates at 35 µg
    Developed using the ECL technique

    Predicted band size : 16 kDa

实验方案

Anti-RPS19 antibody (ab123290)参考文献

ab123290 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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