概述

  • 产品名称Anti-RPIA抗体
    参阅全部 RPIA 一抗
  • 描述
    兔多克隆抗体to RPIA
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide, corresponding to a region within N terminal amino acids 1-50 (QRPGPFSTLYGRVLAPLPGRAGGAASGGGGNSWDLPGSHVRLPGRAQSG T) of Human RPIA, NP_653164

  • 阳性对照
    • 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab86123 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 33 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 通路Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.
  • 疾病相关Defects in RPIA are the cause of ribose 5-phosphate isomerase deficiency (RPID) [MIM:608611]. A patient has been described with a deficiency of ribose 5-phosphate isomerase who presented with leukoencephalopathy and peripheral neuropathy. Proton magnetic resonance spectroscopy of the brain revealed a highly elevated level of the polyols ribitol and D-arabitol, which were subsequently also found in high concentrations in body fluids. Deficient activity of RPIA, one of the pentose phosphate pathway enzymes, has been demonstrated in fibroblasts.
  • 序列相似性Belongs to the ribose 5-phosphate isomerase family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EC 5.3.1.6 antibody
    • MGC103524 antibody
    • Phosphoriboisomerase A antibody
    • Phosphoriboisomerase antibody
    • Ribose 5 phosphate isomerase antibody
    • ribose 5-phosphate epimerase antibody
    • ribose 5-phosphate isomerase A antibody
    • Ribose-5-phosphate isomerase antibody
    • RPI antibody
    • rpiA antibody
    • RPIA_HUMAN antibody
    • zgc:103524 antibody
    see all

Anti-RPIA antibody 图像

  • Anti-RPIA antibody (ab86123) at 1 µg/ml + 293T cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 33 kDa
    Observed band size : 33 kDa

Anti-RPIA antibody (ab86123)参考文献

ab86123 has not yet been referenced specifically in any publications.

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