Synthetic peptide corresponding to a region within C terminal amino acids 211-241 of Human RPH3AL (NP_008918.1), conjugated to KLH.
- 存放说明Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
- 存储溶液Preservative: 0.09% Sodium Azide
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- 纯度Immunogen affinity purified
- 纯化说明Purified through a protein A column, followed by peptide affinity purification.
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The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||1/100 - 1/500. Predicted molecular weight: 34 kDa.
- 功能Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells (By similarity). Acts as a potential RAB3B effector protein in epithelial cells.
- 组织特异性Moderate to high levels of expression in thyroid, ovary, stomach, heart, pancreas, skeletal muscle, kidney and liver. Also detected in epithelial cells.
- 序列相似性Contains 1 FYVE-type zinc finger.
Contains 1 RabBD (Rab-binding) domain.
- 结构域The N-terminus of the RabBD domain is necessary and sufficient for interaction with RAB27A.
- 细胞定位Cytoplasm. Cytoplasmic vesicle > secretory vesicle membrane. Recruited to the vesicle membrane in a GTP-and RAB3B-dependent manner in epithelial cells.
Information by UniProt
- Gm1753 antibody
- No C2 domains protein antibody
- Noc2 antibody
Anti-RPH3AL antibody (ab108048)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"