Anti-RP105抗体[RP/14] (ab33758)
- 数据表
- 具体的参考文献 (1)
- 实验方案
概述
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产品名称Anti-RP105抗体[RP/14]
参阅全部 RP105 一抗 -
描述大鼠单克隆抗体[RP/14] to RP105
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宿主Rat
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经测试应用适用于: Flow Cytmore details
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种属反应性与反应: Mouse
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免疫原
The details of the immunogen for this antibody are not available.
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常规说明
Cross linking of CD180 with clone RP/14 has been reported to induce resistance against irradiation induced apoptosis, B-cell proliferation and up-regulation of a co-stimulatory molecule B7.2.
性能
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形式Liquid
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存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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存储溶液Preservative: 0.09% Sodium Azide
Constituents: PBS -
Concentration information loading... -
纯度Protein A purified
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Primary antibody说明Cross linking of CD180 with clone RP/14 has been reported to induce resistance against irradiation induced apoptosis, B-cell proliferation and up-regulation of a co-stimulatory molecule B7.2.
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克隆单克隆
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克隆编号RP/14
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同种型IgG2a
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研究领域
相关产品
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Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab33758 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
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| Flow Cyt | Use 10µl for 106 cells. Use 10µl to label 106 cells in 100µl.
ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
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靶标
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功能May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells.
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组织特异性Expressed mainly on mature peripherical B cells. Detected in spleen, lymph node and appendix. Not detected in pre-B and -T cells.
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序列相似性Belongs to the Toll-like receptor family.
Contains 19 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain. -
细胞定位Cell membrane.
- Information by UniProt
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数据库链接
- Entrez Gene: 17079 Mouse
- SwissProt: Q62192 Mouse
- Unigene: 373974 Mouse
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别名
- CD180 antibody
- CD180 antigen antibody
- CD180_HUMAN antibody
see all
文献
This product has been referenced in:
- Nagai Y et al. Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide. Blood 99:1699-705 (2002). Read more (PubMed: 11861286) »
客户评价及客户问答
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"