Anti-RP105抗体[RP/14] (ab33758)

概述

• 产品名称
  Anti-RP105抗体[RP/14]
  参阅全部 RP105 一抗
• 描述
  大鼠单克隆抗体[RP/14] to RP105
• 经测试应用
  适用于: Flow Cytmore details
• 种属反应性
  与反应: Mouse
  
• 免疫原

  The details of the immunogen for this antibody are not available.

• 常规说明

  
  

  Cross linking of CD180 with clone RP/14 has been reported to induce resistance against irradiation induced apoptosis, B-cell proliferation and up-regulation of a co-stimulatory molecule B7.2.

性能

• 形式
  Liquid
• 存放说明
  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
• 存储溶液
  Preservative: 0.09% Sodium Azide
  Constituents: PBS
• Concentration information loading...
• 纯度
  Protein A purified
• Primary antibody说明
  Cross linking of CD180 with clone RP/14 has been reported to induce resistance against irradiation induced apoptosis, B-cell proliferation and up-regulation of a co-stimulatory molecule B7.2.
• 克隆
  单克隆
• 克隆编号
  RP/14
• 同种型
  IgG2a
• 研究领域
  • Immunology
  • Innate Immunity
  • Macrophage / Inflamm.

  • Immunology
  • Adaptive Immunity
  • B Cells
  • CD

  • Immunology
  • Adaptive Immunity
  • B Cells
  • Non-CD

  • Microbiology
  • Protein
  • Human Protein
  • Defensin

相关产品

• Compatible Secondaries
  • Goat Anti-Rat IgG H&L (Alexa Fluor® 488) (ab150157)
  • Goat Anti-Rat IgG H&L (HRP) (ab205720)

应用

靶标

• 功能
  May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells.
• 组织特异性
  Expressed mainly on mature peripherical B cells. Detected in spleen, lymph node and appendix. Not detected in pre-B and -T cells.
• 序列相似性
  Belongs to the Toll-like receptor family.
  Contains 19 LRR (leucine-rich) repeats.
  Contains 1 LRRCT domain.
• 细胞定位
  Cell membrane.

• Target information above from: UniProt accession Q99467 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 17079 Mouse
  • SwissProt: Q62192 Mouse
  • Unigene: 373974 Mouse
• 别名
  • CD180 antibody
  • CD180 antigen antibody
  • CD180_HUMAN antibody

  • F630107B15 antibody
  • LY64 antibody
  • Ly78 antibody
  • Lymphocyte antigen 64 antibody
  • lymphocyte antigen 64 radioprotective 105kDa antibody
  • lymphocyte antigen-64, radioprotective, 105kDa antibody
  • MGC126233 antibody
  • MGC126234 antibody
  • Radioprotective 105 kDa protein antibody
  • RP105 antibody

  see all

实验方案

• Flow cytometry protocols