概述
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产品名称Anti-RP105抗体[G28-8]
参阅全部 RP105 一抗 -
描述小鼠单克隆抗体[G28-8] to RP105
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宿主Mouse
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经测试应用适用于: IP, Functional Studies, Flow Cytmore details
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种属反应性与反应: Human
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免疫原
Human tonsillar B cells
性能
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形式Liquid
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存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term.
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存储溶液pH: 7.40
Preservative: 0.01% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度Protein A purified
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纯化说明Purity > 95% (by SDS-PAGE)
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克隆单克隆
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克隆编号G28-8
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同种型IgG1
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研究领域
相关产品
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Alternative Versions
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Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab111150 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IP | Use at an assay dependent concentration. | |
| Functional Studies | Use at an assay dependent concentration. Induction of B cell proliferation. | |
| Flow Cyt | Use a concentration of 2 µg/ml. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
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靶标
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功能May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells.
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组织特异性Expressed mainly on mature peripherical B cells. Detected in spleen, lymph node and appendix. Not detected in pre-B and -T cells.
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序列相似性Belongs to the Toll-like receptor family.
Contains 19 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain. -
细胞定位Cell membrane.
- Information by UniProt
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数据库链接
- Entrez Gene: 4064 Human
- Omim: 602226 Human
- SwissProt: Q99467 Human
- Unigene: 87205 Human
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别名
- CD180 antibody
- CD180 antigen antibody
- CD180_HUMAN antibody
see all
文献
ab111150 has not yet been referenced specifically in any publications.
客户评价及客户问答
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"