概述

  • 产品名称Anti-RP105抗体
    参阅全部 RP105 一抗
  • 描述
    兔多克隆抗体to RP105
  • 经测试应用适用于: IHC-Fr, IHC-P, IHC (PFA fixed), WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic 14 amino acid peptide from near the carboxy terminus of human RP105 .

  • 阳性对照
    • Human spleen tissue, human spleen tissue lysate.

性能

应用

Our Abpromise guarantee covers the use of ab45429 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr Use at an assay dependent concentration. PubMed: 24945347
IHC-P Use a concentration of 10 µg/ml.
IHC (PFA fixed) Use at an assay dependent concentration.
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 74 kDa.

靶标

  • 功能May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells.
  • 组织特异性Expressed mainly on mature peripherical B cells. Detected in spleen, lymph node and appendix. Not detected in pre-B and -T cells.
  • 序列相似性Belongs to the Toll-like receptor family.
    Contains 19 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD180 antibody
    • CD180 antigen antibody
    • CD180_HUMAN antibody
    • F630107B15 antibody
    • LY64 antibody
    • Ly78 antibody
    • Lymphocyte antigen 64 antibody
    • lymphocyte antigen 64 radioprotective 105kDa antibody
    • lymphocyte antigen-64, radioprotective, 105kDa antibody
    • MGC126233 antibody
    • MGC126234 antibody
    • Radioprotective 105 kDa protein antibody
    • RP105 antibody
    see all

Anti-RP105 antibody 图像

  • Immunohistochemistry of RP105 in human spleen tissue with ab45429 at 10 µg/ml.
  • Lane 1 : Anti-RP105 antibody (ab45429) at 0.5 µg/ml
    Lane 2 : Anti-RP105 antibody (ab45429) at 1 µg/ml

    Lane 1 : Human spleen tissue lysate
    Lane 2 : Human spleen tissue lysate

    Lysates/proteins at 15 µg per lane.

    Secondary
    anti-rabbit IgG HRP at 1/10000 dilution

    Predicted band size : 74 kDa
    Observed band size : 90 kDa (why is the actual band size different from the predicted?)

Anti-RP105 antibody (ab45429)参考文献

This product has been referenced in:
  • Bastiaansen AJ  et al. TLR4 Accessory Molecule RP105 (CD180) Regulates Monocyte-Driven Arteriogenesis in a Murine Hind Limb Ischemia Model. PLoS One 9:e99882 (2014). IHC-P, IHC-Fr ; Mouse . Read more (PubMed: 24945347) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab45429.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"