概述

  • 产品名称Anti-ROM1抗体
    参阅全部 ROM1 一抗
  • 描述
    兔多克隆抗体to ROM1
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Cow, Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 216-265 (CCNPHSPRPC LQNRLSDSYA HPLFDPRQPN QNLWAQGCHE VLLEHLQDLA) of human ROM1 (NP_000318)

  • 阳性对照
    • Transfected 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab80507 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 37 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1/312500.

靶标

  • 功能May function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. It is essential for disk morphogenesis.
  • 组织特异性Retina (photoreceptor). In rim region of ROS (rod outer segment) disks.
  • 疾病相关Defects in ROM1 may cause retinitis pigmentosa (RP) [MIM:268000]; when associated with defects in PRPH2.
  • 序列相似性Belongs to the PRPH2/ROM1 family.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Retinal outer segment membrane protein 1 antibody
    • Rod outer segment membrane protein 1 antibody
    • ROM antibody
    • ROM1 antibody
    • ROM1_HUMAN antibody
    • ROSP1 antibody
    • RP7 antibody
    • Tetraspanin 23 antibody
    • Tetraspanin-23 antibody
    • Tspan 23 antibody
    • Tspan-23 antibody
    • TSPAN23 antibody
    see all

Anti-ROM1 antibody 图像

  • Anti-ROM1 antibody (ab80507) at 1/1 dilution + transfected 293T cell lysate at 10 µg with 5% skim milk / PBS buffer

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 37 kDa
    Observed band size : 47 kDa (why is the actual band size different from the predicted?)

Anti-ROM1 antibody (ab80507)参考文献

This product has been referenced in:
  • Kevany BM  et al. Structural and functional analysis of the native peripherin-ROM1 complex isolated from photoreceptor cells. J Biol Chem 288:36272-84 (2013). WB ; Cow . Read more (PubMed: 24196967) »

See 1 Publication for this product

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