概述

  • 产品名称Anti-RNF70抗体
  • 描述
    小鼠单克隆抗体to RNF70
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    Recombinant fragment: DSESSGTNLN IDNEDYSRYP PREYRASGSR RGMAYGHIDS YGADDSEEEG AGPVERPPVR GKTGKFKDDK LYDPEKGARS LAGPPPHFSS FSRDVREERD , corresponding to amino acids 81-181 of Human RNF70

性能

应用

Our Abpromise guarantee covers the use of ab56395 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Has E2-dependent E3 ubiquitin-protein ligase activity. Ubiquitinates MAGED1 antigen leading to its subsequent degradation by proteasome (By similarity). May be involved in protein sorting.
    • 组织特异性Expressed in various regions of the brain including the cerebellum, cerebral cortex, medulla, occipital pole, frontal lobe, temporal lobe and putamen. Highest levels in the cerebral cortex.
    • 序列相似性Contains 1 RING-type zinc finger.
    • 结构域The RING-type zinc finger domain interacts with an ubiquitin-conjugating enzyme (E2) and facilitates ubiquitination.
    • 翻译后修饰Substrate for E2-dependent ubiquitination.
    • Information by UniProt
    • 数据库链接
    • 别名
      • E3 ubiquitin-protein ligase Praja 1 antibody
      • E3 ubiquitin-protein ligase Praja-1 antibody
      • PJA1 antibody
      • PJA1_HUMAN antibody
      • PRAJA 1 antibody
      • Praja ring finger 1 antibody
      • Praja1 antibody
      • RING finger protein 70 antibody
      • RNF 70 antibody
      • RP23-414J22.4 antibody
      see all

    Anti-RNF70 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab56395 RNF70 antibody at 1ug/ml. Predicted band size of the tagged immunogen is 37 kDa. The immunogen alone is 11.2 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Anti-RNF70 antibody (ab56395)参考文献

    ab56395 has not yet been referenced specifically in any publications.

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