Anti-RNF3 (247 aa isoform)抗体(ab3892)

概述

  • 产品名称
    Anti-RNF3 (247 aa isoform)抗体
  • 描述
    山羊多克隆抗体to RNF3 (247 aa isoform)
  • 特异性
    This antibody is expected to recognise the 247 aa isoform (NP_006306) only, not the 132 aa isoform (NP_694982).
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide: PLLLHYRPKMDLL, corresponding to C terminal amino acids 230-242 of Human RNF3 (247 aa isoform).

  • 阳性对照
    • Human Heart lysate.
  • 常规说明
    Principal Names – RNF3; DONG1; RNF3A; MGC40413; ring finger protein 3 Official Gene Symbol - RNF3 GenBank Accession Number – NP_006306 LocusLink ID - 10336 (human); 69587 (mouse).

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度
    IgG fraction
  • 纯化说明
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab3892 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 - 2 µg/ml. Can be blocked with Human RNF3 (247 aa isoform) peptide (ab22965).

靶标

  • 功能
    Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
  • 序列相似性
    Contains 1 RING-type zinc finger.
  • 细胞定位
    Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZp686D20235 antibody
    • DONG1 antibody
    • FLJ36550 antibody
    • FLJ43813 antibody
    • MGC129615 antibody
    • MGC40413 antibody
    • PCGF3 antibody
    • PCGF3_HUMAN antibody
    • polycomb group ring finger 3 antibody
    • Polycomb group RING finger protein 3 antibody
    • Ring finger protein 3 antibody
    • RING finger protein 3A antibody
    • RNF3 antibody
    • RNF3A antibody
    see all

图片

  • ab3892 staining (1µg/ml) of Human Heart lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

实验方案

文献

ab3892 has not yet been referenced specifically in any publications.

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