概述

  • 产品名称Anti-RNF23抗体
    参阅全部 RNF23 一抗
  • 描述
    兔多克隆抗体to RNF23
  • 特异性This antibody is specific for RNF23.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Dog, Pig, Chimpanzee
  • 免疫原

    A region within synthetic peptide: QHHEALSLFC YEDQEAVCLI CAISHTHRAH TVVPLDDATQ EYKEKLQKCL, corresponding to N terminal amino acids 109-158 of Human RNF23

  • 阳性对照
    • HepG2 cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab49312 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1.25 mg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 60 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1:12500

靶标

  • 功能May facilitate apoptosis by inhibiting the poly-ubiquitination and subsequent proteasome-mediated degradation of the pro-apoptotic protein MOAP1.
  • 组织特异性Ubiquitous; highly expressed in brain, heart, kidney, liver, skeletal muscle, spleen and testis.
  • 序列相似性Belongs to the TRIM/RBCC family.
    Contains 1 B box-type zinc finger.
    Contains 1 B30.2/SPRY domain.
    Contains 1 RING-type zinc finger.
  • 细胞定位Cytoplasm > cytosol. Mitochondrion. Found predominantly in the cytosol. Partial shift from the cytosol to the mitochondria when co-localized with MOAP1.
  • Information by UniProt
  • 数据库链接
  • 别名
    • HGNC:10065 antibody
    • MGC32984 antibody
    • RING finger protein 23 antibody
    • RNF23 antibody
    • Testis abundant finger protein antibody
    • Testis-abundant finger protein antibody
    • TFP antibody
    • TFP RING FINGER PROTEIN 23 antibody
    • TRI39_HUMAN antibody
    • Trim39 antibody
    • TRIM39B antibody
    • Tripartite motif containing 39 antibody
    • Tripartite motif-containing protein 39 antibody
    see all

Anti-RNF23 antibody 图像

  • Anti-RNF23 antibody (ab49312) at 1.25 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 60 kDa
    Observed band size : 50 kDa (why is the actual band size different from the predicted?)

Anti-RNF23 antibody (ab49312)参考文献

ab49312 has not yet been referenced specifically in any publications.

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