产品名称 Anti-RNF22抗体 参阅全部 RNF22 一抗
IP more details 不适用于:
Rat, Rabbit, Guinea pig, Cow, Dog, Chimpanzee, Ferret, Gorilla, Chinese hamster, Orangutan
Synthetic peptide corresponding to a region between residues 50 and 100 of human RNF22 (NP_006449.2)
存放说明 Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
存储溶液 Preservative: 0.09% Sodium Azide
Constituents: 8mM PBS, 60mM Citrate, 150mM Tris, pH 7-8
Concentration information loading...
纯度 Immunogen affinity purified
纯化说明 ab74190 was affinity purified using an epitope specific to RNF22 immobilized on solid support.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at 2-5 µg/mg of lysate.
应用说明 Is unsuitable for WB.
功能 Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.
组织特异性 Expressed in brain, heart, uterus and testis.
序列相似性 Belongs to the TRIM/RBCC family. Contains 1 B box-type zinc finger. Contains 1 filamin repeat. Contains 6 NHL repeats. Contains 1 RING-type zinc finger.
结构域 The interaction with MYO5B is dependent upon its NHL repeats, which form a beta-propeller (NHL) domain containing six blades.
细胞定位 Cytoplasm. Early endosome.
Information by UniProt
Brain expressed ring finger antibody
Brain-expressed RING finger protein antibody
Anti-RNF22 antibody 图像
Immunoprecipitation - RNF22 antibody (ab74190)
Detection of RNF22 by Western Blot of Immunprecipitate.
anit-RNF22 ( ab74191) at 1µg/ml staining RNF22 in HeLa whole cell lysate immunoprecipitated using ab74190 at 3µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Detection: Chemiluminescence with exposure time of 30 seconds.
Anti-RNF22 antibody (ab74190)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"