产品名称 Anti-RNF22抗体 参阅全部 RNF22 一抗
WB, IHC-P more details
Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Zebrafish
Synthetic peptide: ALVSDLETIC GAKQKVLQSQ LDTLRQGQEH IGSSCSFAEQ ALRLGSAPEV , corresponding to amino acids 218-267 of Human RNF22
HepG2 cell lysate, human kidney tissue.
存放说明 Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
存储溶液 Preservative: None
Constituents: 2% Sucrose, PBS
Concentration information loading...
纯度 Protein A purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Detects a band of approximately 60 kDa (predicted molecular weight: 81 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
Use a concentration of 4 - 8 µg/ml.
功能 Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.
组织特异性 Expressed in brain, heart, uterus and testis.
序列相似性 Belongs to the TRIM/RBCC family. Contains 1 B box-type zinc finger. Contains 1 filamin repeat. Contains 6 NHL repeats. Contains 1 RING-type zinc finger.
结构域 The interaction with MYO5B is dependent upon its NHL repeats, which form a beta-propeller (NHL) domain containing six blades.
细胞定位 Cytoplasm. Early endosome.
Information by UniProt
Brain expressed ring finger antibody
Brain-expressed RING finger protein antibody
Anti-RNF22 antibody 图像
Western blot - RNF22 antibody (ab66612)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-RNF22 antibody(ab66612)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human kidney tissue labelling RNF22 with ab66612 at 4-8µg/ml. Arrows indicate positively labelled epithelial cells of the renal tubule. Magnification: 400X.
Anti-RNF22 antibody (ab66612)参考文献
has not yet been referenced specifically in any publications.
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