概述

  • 产品名称
  • 描述
    兔多克隆抗体to RNF167
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within intracellular amino acids 179-228 (GIVGLLVLAM GAVMIARCIQ HRKRLQRNRL TKEQLKQIPT HDYQKGDQYD) of Human RNF167 (NP_056343).

  • 阳性对照
    • HeLa Cell Lysate

性能

应用

Our Abpromise guarantee covers the use of ab105568 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 38 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition.
  • 组织特异性
    Strongly expressed in the kidney and liver (at protein level).
  • 通路
    Protein modification; protein ubiquitination.
  • 序列相似性
    Contains 1 PA (protease associated) domain.
    Contains 1 RING-type zinc finger.
  • 翻译后修饰
    Auto-ubiquitinated in vitro in the presence of UBE2D1 and UBE2E1.
  • 细胞定位
    Endomembrane system. Targeted to cytoplasmic membranes.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 5730408C10Rik antibody
    • E3 ubiquitin-protein ligase RNF167 antibody
    • LP2254 antibody
    • RING finger protein 167 antibody
    • RING105 antibody
    • RN167_HUMAN antibody
    • RNF167 antibody
    see all

图片

  • Anti-RNF167 antibody (ab105568) at 1 µg/ml + HeLa Cell Lysate at 10 µg

    Predicted band size : 38 kDa

实验方案

文献

ab105568 has not yet been referenced specifically in any publications.

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