概述

  • 产品名称Anti-RNF14抗体
    参阅全部 RNF14 一抗
  • 描述
    兔多克隆抗体to RNF14
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Rat
    预测可用于: Mouse, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Human, Pig, Rhesus monkey, Orangutan
  • 免疫原

    Synthetic peptide: SAEDLEAQED ELLALASIYD GDEFRKAESV QGGETRIYLD LPQNFKIFVS , corresponding to a region within the N terminal amino acids 2-51 of Human RNF14.

  • 阳性对照
    • Rat liver lysate

性能

应用

Our Abpromise guarantee covers the use of ab113845 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 54 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which could be nuclear proteins. Could play a role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription.
  • 组织特异性Widely expressed.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Belongs to the RBR family. RNF14 subfamily.
    Contains 1 IBR-type zinc finger.
    Contains 2 RING-type zinc fingers.
    Contains 1 RWD domain.
  • 结构域The N-terminal destruction box (D-box) acts as a recognition signal for degradation via the ubiquitin-proteasome pathway.
    The RING-type zinc finger is essential for the interaction with UBE2E2.
  • 翻译后修饰RING-type zinc finger-dependent and UBE2E2-dependent autoubiquitination.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Androgen receptor associated protein 54 antibody
    • Androgen receptor-associated protein 54 antibody
    • ARA 54 antibody
    • ARA54 antibody
    • E3 ubiquitin protein ligase RNF14 antibody
    • E3 ubiquitin-protein ligase RNF14 antibody
    • FLJ26004 antibody
    • HFB 30 antibody
    • HFB30 antibody
    • HRIHFB2038 antibody
    • RING finger protein 14 antibody
    • RNF 14 antibody
    • Rnf14 antibody
    • RNF14_HUMAN antibody
    • TRIAD 2 antibody
    • TRIAD2 antibody
    • Triad2 protein antibody
    see all

Anti-RNF14 antibody 图像

  • Anti-RNF14 antibody (ab113845) at 1 µg/ml + Rat liver lysate at 10 µg

    Predicted band size : 54 kDa

Anti-RNF14 antibody (ab113845)参考文献

ab113845 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab113845.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"