产品名称 Anti-RNF14抗体 参阅全部 RNF14 一抗
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Synthetic peptide:corresponding to amino acids 380-430( G KRVIQKAL EE MESKEWL EKN SKSCPC CGTP IEKLD GCNKM TCTGCMQYFC)of Human RNF14
Extracts from RAW264.7 cells
存放说明 Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
存储溶液 pH: 7.40 Preservative: 0.02% Sodium azide Constituents: PBS, 0.88% Sodium chloride, 50% Glycerol
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纯度 Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Predicted molecular weight: 54 kDa.
功能 Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which could be nuclear proteins. Could play a role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription.
组织特异性 Widely expressed.
通路 Protein modification; protein ubiquitination.
序列相似性 Belongs to the RBR family. RNF14 subfamily. Contains 1 IBR-type zinc finger. Contains 2 RING-type zinc fingers. Contains 1 RWD domain.
结构域 The N-terminal destruction box (D-box) acts as a recognition signal for degradation via the ubiquitin-proteasome pathway. The RING-type zinc finger is essential for the interaction with UBE2E2.
翻译后修饰 RING-type zinc finger-dependent and UBE2E2-dependent autoubiquitination.
细胞定位 Cytoplasm. Nucleus.
Information by UniProt
Androgen receptor associated protein 54 antibody
Androgen receptor-associated protein 54 antibody
ARA 54 antibody
Anti-RNF14 antibody (ab110395)参考文献
has not yet been referenced specifically in any publications.
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