概述

  • 产品名称Anti-RNF14抗体
    参阅全部 RNF14 一抗
  • 描述
    兔多克隆抗体to RNF14
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat, Human
  • 免疫原

    Synthetic peptide:corresponding to amino acids 380-430( G KRVIQKAL EE MESKEWL EKN SKSCPC CGTP IEKLD GCNKM TCTGCMQYFC)of Human RNF14

  • 阳性对照
    • Extracts from RAW264.7 cells

性能

应用

Our Abpromise guarantee covers the use of ab110395 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 54 kDa.

靶标

  • 功能Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which could be nuclear proteins. Could play a role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription.
  • 组织特异性Widely expressed.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Belongs to the RBR family. RNF14 subfamily.
    Contains 1 IBR-type zinc finger.
    Contains 2 RING-type zinc fingers.
    Contains 1 RWD domain.
  • 结构域The N-terminal destruction box (D-box) acts as a recognition signal for degradation via the ubiquitin-proteasome pathway.
    The RING-type zinc finger is essential for the interaction with UBE2E2.
  • 翻译后修饰RING-type zinc finger-dependent and UBE2E2-dependent autoubiquitination.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Androgen receptor associated protein 54 antibody
    • Androgen receptor-associated protein 54 antibody
    • ARA 54 antibody
    • ARA54 antibody
    • E3 ubiquitin protein ligase RNF14 antibody
    • E3 ubiquitin-protein ligase RNF14 antibody
    • FLJ26004 antibody
    • HFB 30 antibody
    • HFB30 antibody
    • HRIHFB2038 antibody
    • RING finger protein 14 antibody
    • RNF 14 antibody
    • Rnf14 antibody
    • RNF14_HUMAN antibody
    • TRIAD 2 antibody
    • TRIAD2 antibody
    • Triad2 protein antibody
    see all

Anti-RNF14 antibody 图像

  • All lanes : Anti-RNF14 antibody (ab110395) at 1/500 dilution

    Lane 1 : Extracts from RAW264.7 cells
    Lane 2 : Extracts from RAW264.7 cells with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 54 kDa

Anti-RNF14 antibody (ab110395)参考文献

ab110395 has not yet been referenced specifically in any publications.

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