概述

  • 产品名称
    Anti-RND3抗体[4]
    参阅全部 RND3 一抗
  • 描述
    小鼠单克隆抗体[4] to RND3
  • 经测试应用
    适用于: WB, ICC/IF, IHC-Frmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Purified recombinant full length RND3

  • 阳性对照
    • HMVEC total cell extract.
  • 常规说明


    Monoclonal antibodies specific for RhoE(Rnd3) are an important tool for studying cell motility and cytoskeleton organization.

    Abcam is committed to meeting high standards of ethical manufacturing and has decided to discontinue this product by July 2018 as it has been generated by the ascites method. We are sorry for any inconvenience this may cause. 

性能

应用

Our Abpromise guarantee covers the use of ab50316 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 4 - 8 µg/ml. Predicted molecular weight: 27 kDa.
ICC/IF 1/200. PubMed: 19349584
IHC-Fr 1/200. PubMed: 19349584

靶标

  • 功能
    Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.
  • 组织特异性
    Ubiquitous.
  • 序列相似性
    Belongs to the small GTPase superfamily. Rho family.
  • 细胞定位
    Golgi apparatus membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ARHE antibody
    • memB antibody
    • Protein MemB antibody
    • Ras homolog gene family member E antibody
    • Rho family GTPase 3 antibody
    • Rho-related GTP-binding protein Rho8 antibody
    • Rho-related GTP-binding protein RhoE antibody
    • Rho8 antibody
    • RhoE antibody
    • Rnd3 antibody
    • RND3_HUMAN antibody
    • Small GTP binding protein Rho8 antibody
    see all

文献

This product has been referenced in:
  • Pacary E  et al. Rnd3 coordinates early steps of cortical neurogenesis through actin-dependent and -independent mechanisms. Nat Commun 4:1635 (2013). IHC-Fr ; Mouse . Read more (PubMed: 23535656) »
  • Pacary E  et al. Proneural transcription factors regulate different steps of cortical neuron migration through Rnd-mediated inhibition of RhoA signaling. Neuron 69:1069-84 (2011). ICC/IF ; Mouse . Read more (PubMed: 21435554) »

See all 4 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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