Anti-RNA polymerase II RPB4抗体(ab57301)

概述

  • 产品名称Anti-RNA polymerase II RPB4抗体
    参阅全部 RNA polymerase II RPB4 一抗
  • 描述
    小鼠单克隆抗体to RNA polymerase II RPB4
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-143 of Human RNA polymerase II RPB4

性能

应用

Our Abpromise guarantee covers the use of ab57301 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB4 is part of a subcomplex with RPB7 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA.
    • 序列相似性Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • DNA directed RNA polymerase II 16 kDa polypeptide antibody
      • DNA directed RNA polymerase II subunit D antibody
      • DNA directed RNA polymerase II subunit RPB4 antibody
      • DNA-directed RNA polymerase II 16 kDa polypeptide antibody
      • DNA-directed RNA polymerase II subunit D antibody
      • DNA-directed RNA polymerase II subunit rpb4 antibody
      • HSRBP4 antibody
      • polr2d antibody
      • polymerase RNA II DNA directed polypeptide D antibody
      • RBP4 antibody
      • RNA polymerase II 16 kDa subunit antibody
      • RNA polymerase II subunit B4 antibody
      • RNA polymerase II subunit D antibody
      • RNA polymerase II subunit hsRBP4 antibody
      • RPB16 antibody
      • RPB4_HUMAN antibody
      see all

    Anti-RNA polymerase II RPB4 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab57301 RNA polymerase II RPB4 antibody at 1ug/ml. Predicted band size of immunogen is 41 kDa

    Anti-RNA polymerase II RPB4 antibody (ab57301)参考文献

    ab57301 has not yet been referenced specifically in any publications.

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