Anti-RLTPR抗体(ab122717)
Key features and details
- Rabbit polyclonal to RLTPR
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-RLTPR抗体
参阅全部 RLTPR 一抗 -
描述
兔多克隆抗体to RLTPR -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
antigen sequence: EVNELCQSVQ EHVELLGCGA GPQGEAAVRQ AEDAIQNANF SLSILPILYE AGSSPSHHWQ LGQKLEGLLR QVGEVCRQDI QDFTQ, corresponding to amino acids 729-813 of Human RLTPR.
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阳性对照
- Human rectum tissue
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常规说明
ab122717 is mono-specific.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 59% PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
Primary antibody说明
ab122717 is mono-specific. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab122717于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P |
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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说明 |
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IHC-P
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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组织特异性
Expressed in all tissues tested, including thymus, spleen, colon, leukocytes, peripheral blood, skin, skin keratinocytes and skin fibroblasts. -
序列相似性
Belongs to the CARMIL family.
Contains 16 LRR (leucine-rich) repeats. -
发展阶段
Expressed in fetal skin. - Information by UniProt
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数据库链接
- Entrez Gene: 146206 Human
- Omim: 610859 Human
- SwissProt: Q6F5E8 Human
- Unigene: 611432 Human
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别名
- CARMIL2 antibody
- CARMIL2b antibody
- Leucine rich repeat containing 16C antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (5)
ab122717 被引用在 5 文献中.
- Uchida Y et al. RLTPR Q575E: A novel recurrent gain-of-function mutation in patients with adult T-cell leukemia/lymphoma. Eur J Haematol 106:221-229 (2021). PubMed: 33098696
- Shamriz O et al. Exogenous interleukin-2 can rescue in-vitro T cell activation and proliferation in patients with a novel capping protein regulator and myosin 1 linker 2 mutation. Clin Exp Immunol 200:215-227 (2020). PubMed: 32201938
- Alazami AM et al. Novel CARMIL2 Mutations in Patients with Variable Clinical Dermatitis, Infections, and Combined Immunodeficiency. Front Immunol 9:203 (2018). PubMed: 29479355
- Park J et al. Genomic analysis of 220 CTCLs identifies a novel recurrent gain-of-function alteration in RLTPR (p.Q575E). Blood 130:1430-1440 (2017). PubMed: 28694326
- Schober T et al. A human immunodeficiency syndrome caused by mutations in CARMIL2. Nat Commun 8:14209 (2017). WB ; Human . PubMed: 28112205