概述

  • 产品名称Anti-RIN1抗体
    参阅全部 RIN1 一抗
  • 描述
    兔多克隆抗体to RIN1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length protein, corresponding to amino acids 1-783 of Human RIN1 (NP_004283.2).

  • 阳性对照
    • IMR-32 cell lysate and RIN1 transfected 293T cell line lysate

性能

应用

Our Abpromise guarantee covers the use of ab103151 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 84 kDa.

靶标

  • 相关性RIN1 is a Ras effector protein which can affect Ras signaling in a variety of ways. It enhances signaling from ABL1 and ABL2 whcih are involved in regulation of cytoskeletal remodeling. It may function as a guanine nucleotide exchange factor in activation of Rab5a. Rin1 also competes with RAF1 for binding of the activated form of Ras. It may play a role inhibiting the modulation of neuronal plasticity in formation of aversive memory, and has been implicated as a tumor supressor gene in breast cancer.
  • 细胞定位Cytoplasmic and Plasma membrane
  • 数据库链接
  • 别名
    • Ras and Rab interactor 1 antibody
    • ras inhibitor 1 antibody
    • ras inhibitor antibody
    • Ras inhibitor JC99 antibody
    • ras inhibitor RIN1 antibody
    • Ras interaction/interference protein 1 antibody
    • RIN 1 antibody
    see all

Anti-RIN1 antibody 图像

  • Anti-RIN1 antibody (ab103151) at 1/500 dilution + IMR-32 cell lysate at 50 µg

    Predicted band size : 84 kDa
  • All lanes : Anti-RIN1 antibody (ab103151) at 1/500 dilution

    Lane 1 : RIN1 transfected 293T cell line
    Lane 2 : Non-transfected 293T cell line

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 84 kDa

Anti-RIN1 antibody (ab103151)参考文献

ab103151 has not yet been referenced specifically in any publications.

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