Anti-Ricin toxin A chain抗体(ab27169)
Key features and details
- Rabbit polyclonal to Ricin toxin A chain
- Suitable for: ELISA, WB, Electron Microscopy
- Reacts with: Castor bean
- Isotype: IgG
概述
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产品名称
Anti-Ricin toxin A chain抗体 -
描述
兔多克隆抗体to Ricin toxin A chain -
宿主
Rabbit -
经测试应用
适用于: ELISA, WB, Electron Microscopymore details -
种属反应性
与反应: Castor bean -
免疫原
Full length native protein: Purified intact A chain from RCA 60.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.097% Sodium azide
Constituents: 0.0268% PBS, 2.9% Sodium chloride -
Concentration information loading...
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纯度
Whole antiserum -
纯化说明
sterile-filtered (0.22 mm pore size) serum with the addition of 15 mM NaN3 -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab27169于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ELISA |
1/20000.
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WB |
1/2000. Predicted molecular weight: 32 kDa.
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Electron Microscopy |
Use at an assay dependent concentration. PubMed: 21886775
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说明 |
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ELISA
1/20000. |
WB
1/2000. Predicted molecular weight: 32 kDa. |
Electron Microscopy
Use at an assay dependent concentration. PubMed: 21886775 |
靶标
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相关性
Ricin chain A (RTA) is a ribosome inactivating enzyme with a molecular weight of 32 kDa. RTA is normally linked by a disulfide bond to the galactose/N acetylgalactosamine binding lectin (34 kDa), also called the B chain or RTB. Together with RTB, RTA constitutes the heterodimeric cytotoxin Ricin (RCA 60) from Ricinus communis. This ricin, which is a type 2 RIP (ribosome inactivating protein) is among the most potent cytotoxins in nature. Ricin is highly toxic to animal cells and to a lesser extent to plant cells. -
别名
- Ricin A chain antibody
- Ricin antibody
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab27169 被引用在 4 文献中.
- Marszalowicz GP et al. GUCY2C lysosomotropic endocytosis delivers immunotoxin therapy to metastatic colorectal cancer. Oncotarget 5:9460-71 (2014). PubMed: 25294806
- Wang W et al. Mannosidase 2, alpha 1 Deficiency Is Associated with Ricin Resistance in Embryonic Stem (ES) Cells. PLoS One 6:e22993 (2011). Electron Microscopy . PubMed: 21886775
- Ray S et al. Modulation of toxin stability by 4-phenylbutyric Acid and negatively charged phospholipids. PLoS One 6:e23692 (2011). PubMed: 21887297
- Yin HQ et al. A nanoparticle-based bio-barcode assay for ultrasensitive detection of ricin toxin. Toxicon : (2011). PubMed: 22005297