概述

  • 产品名称
  • 描述
    兔多克隆抗体to RIC3
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 319-348 of Human RIC3 (NP_001128581.1 , NP_078833.3)

  • 阳性对照
    • NCI-H292 Cell Lysate

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    ab112911 was purified through a protein A column, followed by peptide affinity purification.
  • 克隆
    多克隆
  • 同种型
    IgG

应用

Our Abpromise guarantee covers the use of ab112911 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 41 kDa.

靶标

  • 功能
    Promotes functional expression of homomeric alpha-7 and alpha-8 nicotinic acetylcholine receptors at the cell surface. May also promote functional expression of homomeric serotoninergic 5-HT3 receptors, and of heteromeric acetylcholine receptors alpha-3/beta-2, alpha-3/beta-4, alpha-4/beta-2 and alpha-4/beta-4.
  • 组织特异性
    Broadly expressed, with high levels in muscle, brain and heart. Over-expressed in brains from patients with bipolar disease or schizophrenia.
  • 序列相似性
    Belongs to the ric-3 family.
  • 细胞定位
    Endoplasmic reticulum membrane and Endoplasmic reticulum membrane. Golgi apparatus membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AYST720 antibody
    • FLJ11608 antibody
    • PRO1385 antibody
    • Protein RIC-3 antibody
    • Resistance to inhibitors of cholinesterase 3 homolog antibody
    • Resistant to inhibitor of cholinesterase 3 antibody
    • RIC3 acetylcholine receptor chaperone antibody
    • Ric3 antibody
    • RIC3_HUMAN antibody
    see all

Anti-RIC3 antibody 图像

  • Anti-RIC3 antibody (ab112911) at 1/100 dilution + NCI-H292 Cell Lysate at 35 µg

    Predicted band size : 41 kDa

实验方案

Anti-RIC3 antibody (ab112911)参考文献

This product has been referenced in:
  • Mulcahy MJ  et al. Resistance to Inhibitors of Cholinesterase 3 (Ric-3) Expression Promotes Selective Protein Associations with the Human a7-Nicotinic Acetylcholine Receptor Interactome. PLoS One 10:e0134409 (2015). WB ; Human . Read more (PubMed: 26258666) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab112911.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册