RabMAb

Anti-RhoGDI抗体[EPR3772] (ab108977)

概述

  • 产品名称Anti-RhoGDI抗体[EPR3772]
    参阅全部 RhoGDI 一抗
  • 描述
    兔单克隆抗体[EPR3772] to RhoGDI
  • 经测试应用适用于: WB, ICCmore details
    不适用于: Flow Cyt,IHC-P or IP
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to residues in Human RhoGDI.

  • 阳性对照
    • Jurkat, HeLa, HL-60 and NIH/3T3 cell lysates
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    A trial size is available to purchase for this antibody.

    Alternative versions available:

    Anti-RhoGDI antibody (HRP) [EPR3772] (ab200183)

性能

应用

Our Abpromise guarantee covers the use of ab108977 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/5000. Detects a band of approximately 26 kDa (predicted molecular weight: 23 kDa).
ICC 1/50 - 1/100.
  • 应用说明Is unsuitable for Flow Cyt,IHC-P or IP.
  • 靶标

    • 功能Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
    • 序列相似性Belongs to the Rho GDI family.
    • 细胞定位Cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • ARHGDIA antibody
      • fa96g11 antibody
      • GDIA 1 antibody
      • GDIA1 antibody
      • GDIR1_HUMAN antibody
      • MGC117248 antibody
      • NPHS8 antibody
      • Rho GDI 1 antibody
      • Rho GDI alpha antibody
      • Rho GDI antibody
      • Rho GDP dissociation inhibitor (GDI) alpha antibody
      • Rho GDP dissociation inhibitor 1 antibody
      • Rho GDP dissociation inhibitor alpha antibody
      • Rho GDP-dissociation inhibitor 1 antibody
      • Rho-GDI alpha antibody
      • RhoGDI 1 antibody
      • RhoGDI alpha antibody
      • RHOGDI antibody
      • RhoGDI1 antibody
      • wu:fa96g11 antibody
      • zgc:55554 antibody
      • zgc:77681 antibody
      see all

    Anti-RhoGDI antibody [EPR3772] 图像

    • All lanes : Anti-RhoGDI antibody [EPR3772] (ab108977) at 1/1000 dilution

      Lane 1 : Jurkat cell lysates
      Lane 2 : HeLa cell lysates
      Lane 3 : HL-60 cell lysates
      Lane 4 : NIH/3T3 cell lysates

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 23 kDa
      Observed band size : 26 kDa (why is the actual band size different from the predicted?)

    Anti-RhoGDI antibody [EPR3772] (ab108977)参考文献

    This product has been referenced in:
    • Yentrapalli R  et al. The PI3K/Akt/mTOR pathway is implicated in the premature senescence of primary human endothelial cells exposed to chronic radiation. PLoS One 8:e70024 (2013). Human . Read more (PubMed: 23936371) »

    See 1 Publication for this product

    Product Wall

    Thank you for your email.

    Unfortunately the order is out of Abpromise guarantee period. The order was placed on 17th January 2012, which means it was under 6 month guarantee period until 16th June however the complaint was submitted in August ...

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    Thanks you for your email. I apologize for the delay.

    We unfortunately are unable to find reason why the activity of this antibody is dropping. Also we haven't received any other quality complaint for this antibody so I am sorry we will not be...

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    Thank you very much for sending the information.

    In order to understand the problem better could you provide details how this antibody was stored?

    Was the antibody degradation gradual or it just stopped working after 6 months?
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"