概述

  • 产品名称
    Rhodopsin肽

描述

  • 性质
    Synthetic

相关产品

技术指标

Our Abpromise guarantee covers the use of ab4967 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式
    Liquid
  • 补充说明


    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and bovine rhodopsin, catalog ab3424. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

常规信息

  • 别名
    • CSNBAD1
    • MGC138309
    • MGC138311
    • OPN 2
    • OPN2
    • opsd
    • OPSD_HUMAN
    • opsin 2
    • Opsin 2 rod pigment
    • Opsin-2
    • Opsin2
    • Retinitis Pigmentosa 4
    • Retinitis pigmentosa 4 autosomal dominant
    • RHO
    • Rhodopsin
    • RP 4
    • RP4
    see all
  • 功能
    Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal.
  • 组织特异性
    Rod shaped photoreceptor cells which mediates vision in dim light.
  • 疾病相关
    Retinitis pigmentosa 4
    Night blindness, congenital stationary, autosomal dominant 1
  • 序列相似性
    Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
  • 翻译后修饰
    Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.
    Contains one covalently linked retinal chromophore.
  • 细胞定位
    Membrane. Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to the rod outer segment (OS) photosensory cilia.
  • Information by UniProt

Rhodopsin peptide (ab4967)参考文献

ab4967 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting Abcam in regards to ab4967.
We have never tested this peptide in this particular application, so we cannot say whether it would work in this application or not.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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