Anti-RHOB抗体(ab102770)

概述

  • 产品名称
  • 描述
    兔多克隆抗体to RHOB
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Sheep, Goat, Horse, Chicken, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 107-156 (CPNVPIILVA NKKDLRSDEH VRTELARMKQ EPVRTDDGRA MAVRIQAYDY) of Human RHOB (NP_004031).

  • 阳性对照
    • Human placenta lysate.

性能

应用

Our Abpromise guarantee covers the use of ab102770 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 22 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.
  • 序列相似性
    Belongs to the small GTPase superfamily. Rho family.
  • 翻译后修饰
    Prenylation specifies the subcellular location of RHOB. The farnesylated form is localized to the plasma membrane while the geranylgeranylated form is localized to the endosome.
  • 细胞定位
    Late endosome membrane. Cell membrane. Nucleus. Late endosomal membrane (geranylgeranylated form). Plasma membrane (farnesylated form). Also detected at the nuclear margin and in the nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Aplysia RAS-related homolog 6 antibody
    • ARH6 antibody
    • ARHB antibody
    • H6 antibody
    • MST081 antibody
    • MSTP081 antibody
    • oncogene RHO H6 antibody
    • ras homolog family member B antibody
    • ras homolog gene family, member B antibody
    • Rho cDNA clone 6 antibody
    • Rho related GTP binding protein RhoB Precursor antibody
    • Rho-related GTP-binding protein RhoB antibody
    • Rhob antibody
    • RHOB_HUMAN antibody
    • RHOH6 antibody
    see all

图片

  • Anti-RHOB antibody (ab102770) at 1 µg/ml + Human placenta lysate at 10 µg

    Predicted band size : 22 kDa

实验方案

文献

ab102770 has not yet been referenced specifically in any publications.

客户评价及客户问答

Merci de votre intérêt pour ab102770. A ma connaissance, cet anticorps n’a pas encore été testé en immunohistochimie (IHC) et nous n’offrons pas d’échantillon gratuit à des fins de tests préliminaires. Cependant, si vous souhaitez tester ab102770 en IH...

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