Anti-Rho GTPase-activating protein 24抗体(ab76898)

概述

  • 产品名称Anti-Rho GTPase-activating protein 24抗体
    参阅全部 Rho GTPase-activating protein 24 一抗
  • 描述
    小鼠多克隆抗体to Rho GTPase-activating protein 24
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length Human protein (isoform 3, NP_001036134.1)

  • 阳性对照
    • ARHGAP24-transfected 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab76898 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明ELISA: Use at an assay dependent dilution.
    WB: 1/500 - 1/1000. Predicted molecular weight: 84 kDa (isoform 1).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性ARHGAP24 is a rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. It acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. It controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. There are five different isoforms.Isoform 1 is widely expressed with a higher level in kidney. Isoform 2 is mainly expressed in endothelial cells and is involved in modulation of angiogenesis.
    • 细胞定位Cytoplasmic, cytoskeleton. Cell junction: adherens junction, focal adhesion. Cell projection.
    • 数据库链接
    • 别名
      • ARHGAP24 antibody
      • DKFZP564B1162 antibody
      • Filamin A associated RhoGAP antibody
      • FILGAP antibody
      • FLJ33877 antibody
      • p73 antibody
      • p73RhoGAP antibody
      • RAC1 and CDC4 specific GTPase activating protein of 72kDa antibody
      • RCGAP72 antibody
      • Rho GTPase activating protein 24 antibody
      • Rho type GTPase activating protein 24 antibody
      • RhoGAP of 73 kDa antibody
      • Sarcoma antigen NY SAR 88 antibody
      see all

    Anti-Rho GTPase-activating protein 24 antibody 图像

    • All lanes : Anti-Rho GTPase-activating protein 24 antibody (ab76898) at 1/500 dilution

      Lane 1 : ARHGAP24 (isoform 3) transfected 293T cell lysate
      Lane 2 : Non transfected 293T cell lysate

      Lysates/proteins at 25 µg per lane.

      Secondary
      Goat Anti-Mouse IgG (H&L) HRP-conjugated at 1/5000 dilution

      Predicted band size : 84 kDa
      Observed band size : 75 kDa (why is the actual band size different from the predicted?)

    Anti-Rho GTPase-activating protein 24 antibody (ab76898)参考文献

    ab76898 has not yet been referenced specifically in any publications.

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