概述

  • 产品名称Anti-RHEB抗体[Rheb 3H6]
    参阅全部 RHEB 一抗
  • 描述
    小鼠单克隆抗体[Rheb 3H6] to RHEB
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Human Rheb GST fusion

性能

应用

Our Abpromise guarantee covers the use of ab97894 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 20 kDa.
IP Use a concentration of 5 µg/ml.

靶标

  • 功能Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Activates the protein kinase activity of mTORC1. Has low intrinsic GTPase activity.
  • 组织特异性Ubiquitous. Highest levels observed in skeletal and cardiac muscle.
  • 序列相似性Belongs to the small GTPase superfamily. Rheb family.
  • 翻译后修饰Farnesylation is important for efficiently activating mTORC1-mediated signaling.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Ras homolog enriched in brain 2, formerly antibody
    • GTP binding protein Rheb antibody
    • GTP-binding protein Rheb antibody
    • MGC111559 antibody
    • Ras homolog enriched in brain 2 antibody
    • Ras homolog enriched in brain antibody
    • RHEB 2 antibody
    • Rheb antibody
    • RHEB_HUMAN antibody
    • RHEB2 antibody
    • RHEB2, formerly antibody
    see all

Anti-RHEB antibody [Rheb 3H6] (ab97894)参考文献

This product has been referenced in:
  • Findlay GM  et al. A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling. Biochem J 403:13-20 (2007). Read more (PubMed: 17253963) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"