概述

  • 产品名称
  • 描述
    小鼠多克隆抗体to RGS7
  • 经测试应用
    适用于: WB, Flow Cytmore details
  • 种属反应性
    与反应: Rat, Human
  • 免疫原

    Full length Human RGS7 protein (NP_002915.2).

  • 阳性对照
    • Rat brain tissue lysate. Cell lysate from transfected 293T cells.

性能

应用

Our Abpromise guarantee covers the use of ab88643 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 58 kDa (predicted molecular weight: 58 kDa).
Flow Cyt Use at an assay dependent concentration. ab37355-Mouse polyclonal IgG, is suitable for use as an isotype control with this antibody.

靶标

  • 相关性
    RGS7 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP bound form. Activity on G(o) alpha is specifically enhanced by the RGS6/GNG5 dimer. RGS7 may play a role in synaptic vesicle exocytosis and may play an important role in the rapid regulation of neuronal excitability and the cellular responses to short lived stimulations.
  • 细胞定位
    Cytoplasmic
  • 数据库链接
  • 别名
    • OTTHUMP00000037994 antibody
    • Regulator of G protein signalling 7 antibody
    • Regulator of G-protein signaling 7 antibody
    • Regulator of G-protein signaling RGS7 antibody
    • Regulator of G-protein signalling 7 antibody
    see all

图片

  • ab88643 detecting RGS7 in RGS7-expressing 293 cells (Green) compared with negative control 293 cells (Black) by flow cytometry.
  • Anti-RGS7 antibody (ab88643) at 1 µg/ml + Rat brain tissue lysate at 50 µg

    Predicted band size : 58 kDa
    Observed band size : 58 kDa
  • All lanes : Anti-RGS7 antibody (ab88643) at 1 µg/ml

    Lane 1 : cell lysate from RGS7 transfected 293T cells
    Lane 2 : cell lysate from non transfected 293T cells

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 58 kDa
    Observed band size : 58 kDa

文献

ab88643 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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