兔多克隆抗体to RGS19 - C-terminal
Synthetic peptide within Human RGS19 (C terminal). The exact sequence is proprietary. Conjugated to a protein carrier.
Database link: P49795
WB: RGS19-transfected HEK-293T cell lysate.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 10% Glycerol
Concentration information loading...
Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 25 kDa.
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
Highest expression in lung. Placenta, liver and heart also express high levels of GAIP.
Contains 1 RGS domain.
Fatty acylated. Heavily palmitoylated in the cysteine string motif.
Phosphorylated, mainly on serine residues.
Information by UniProt
G alpha interacting protein antibody
G protein signalling regulator 19 antibody
G protein, alpha-interacting protein antibody
Western blot - Anti-RGS19 antibody - C-terminal (ab228611)
All lanes :
Anti-RGS19 antibody - C-terminal (ab228611) at 1/500 dilution
Lane 1 :
Non-transfected HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) cell lysate
Lane 2 :
RGS19-transfected HEK-293T cell lysate
Developed using the ECL technique
Predicted band size :
has not yet been referenced specifically in any publications.
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