Anti-RGS19抗体(ab229253)
Key features and details
- Rabbit polyclonal to RGS19
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-RGS19抗体 -
描述
兔多克隆抗体to RGS19 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Rhesus monkey -
免疫原
Recombinant fragment within Human RGS19. The exact sequence is proprietary.
Database link: P49795 -
阳性对照
- WB: RGS19-transfected HEK-293T whole cell lysate.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
-
Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab229253于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/5000 - 1/20000. Predicted molecular weight: 25 kDa.
|
说明 |
---|
WB
1/5000 - 1/20000. Predicted molecular weight: 25 kDa. |
靶标
-
功能
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein. -
组织特异性
Highest expression in lung. Placenta, liver and heart also express high levels of GAIP. -
序列相似性
Contains 1 RGS domain. -
翻译后修饰
Fatty acylated. Heavily palmitoylated in the cysteine string motif.
Phosphorylated, mainly on serine residues. -
细胞定位
Membrane. - Information by UniProt
-
数据库链接
- Entrez Gene: 10287 Human
- Entrez Gene: 719265 Rhesus monkey
- Omim: 605071 Human
- SwissProt: P49795 Human
- Unigene: 422336 Human
-
别名
- G alpha interacting protein antibody
- G protein signalling regulator 19 antibody
- G protein, alpha-interacting protein antibody
see all
图片
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
SDS download
-
Datasheet download
文献 (0)
ab229253 尚未被引用在任何文献中。