Anti-RGS16抗体[4C9] (ab119925)

概述

  • 产品名称Anti-RGS16抗体[4C9]
    参阅全部 RGS16 一抗
  • 描述
    小鼠单克隆抗体[4C9] to RGS16
  • 经测试应用适用于: WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein of Human RGS16 produced in HEK293T cells (NP_002919).

  • 阳性对照
    • HEK293T cells transfected with RGS16, Human breast, Human Kidney, Human pancreas and Human endometrium tissues, COS7 cells transiently transfected with RGS16.
  • 常规说明Dilute in PBS (pH7.3) before use.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 48% PBS, 50% Glycerol, 1% BSA
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 克隆编号4C9
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab119925 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/2000. Predicted molecular weight: 23 kDa.
IHC-P 1/150.
ICC/IF 1/100.

靶标

  • 功能Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. May play a role in regulating the kinetics of signaling in the phototransduction cascade.
  • 组织特异性Abundantly expressed in retina with lower levels of expression in most other tissues.
  • 序列相似性Contains 1 RGS domain.
  • 翻译后修饰Palmitoylated on Cys-2 and/or Cys-12.
    Phosphorylation on Tyr-168 upon EGFR stimulation. Enhanced GTPase accelerating (GAP) activity on G(i)-alpha.
  • Information by UniProt
  • 数据库链接
  • 别名
    • A28 RGS14 antibody
    • A28 RGS14P antibody
    • A28-RGS14P antibody
    • HGNC:9997 antibody
    • hRGS-r antibody
    • OTTHUMP00000033147 antibody
    • Regulator of G protein signaling 16 antibody
    • Regulator of G protein signalling 16 antibody
    • Regulator of G-protein signaling 16 antibody
    • Retinal-specific RGS antibody
    • Retinally abundant regulator of G protein signaling antibody
    • Retinally abundant regulator of G-protein signaling antibody
    • RGS 16 antibody
    • RGS R antibody
    • RGS-R antibody
    • Rgs14 antibody
    • RGS16 antibody
    • RGS16_HUMAN antibody
    • RGSR antibody
    see all

Anti-RGS16 antibody [4C9] 图像

  • All lanes : Anti-RGS16 antibody [4C9] (ab119925) at 1/2000 dilution

    Lane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control
    Lane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY RGS16 cDNA

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 23 kDa
    HEK293T cell lysates were generated from transient transfection of the cDNA clone (RC202430)
  • Immunohistochemical staining of paraffin-embedded Human breast tissue using ab119925 at a dilution of 1/150.
  • Immunohistochemical staining of paraffin-embedded Human Kidney tissue using ab119925 at a dilution of 1/150.
  • Immunohistochemical staining of paraffin-embedded Human pancreas tissue using ab119925 at a dilution of 1/150.
  • Immunohistochemical staining of paraffin-embedded Human endometrium tissue using ab119925 at a dilution of 1/150.
  • Immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RGS16 using ab119925 at a dilution of 1/100.

Anti-RGS16 antibody [4C9] (ab119925)参考文献

ab119925 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab119925.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"