概述

  • 产品名称Anti-RGS1抗体
    参阅全部 RGS1 一抗
  • 描述
    山羊多克隆抗体to RGS1
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Horse, Cow, Dog
  • 免疫原

    Synthetic peptide:

    C-NLLNDLQANSLK

    (with a Cysteine residue linker), corresponding to C terminal amino acids 198-209 of Human RGS1 (Q08116).

  • 阳性对照
    • HepG2 lysate, Human Small Intestine and Human Thymus tissues

性能

应用

Our Abpromise guarantee covers the use of ab117077 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 - 2 µg/ml. Predicted molecular weight: 24 kDa.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. This protein may be involved in the regulation of B-cell activation and proliferation.
  • 组织特异性B-cell specific. Expression is relatively low in B-cells and chronic lymphocytic leukemia B-cells; however, in other types of malignant B-cell such as non-Hodgkin lymphoma and hairy cell leukemia, expression is constitutively high.
  • 序列相似性Contains 1 RGS domain.
  • 翻译后修饰Could be phosphorylated. Might be functionally regulated by protein kinase(s).
  • Information by UniProt
  • 数据库链接
  • 别名
    • 1R20 antibody
    • B cell activation protein BL34 antibody
    • B-cell activation protein BL34 antibody
    • BL34 antibody
    • Early response protein 1R20 antibody
    • IER 1 antibody
    • IER1 antibody
    • Immediate early response 1 B cell specific antibody
    • immediate-early response 1, B-cell specific antibody
    • IR20 antibody
    • Regulator of G protein signalling 1 antibody
    • Regulator of G-protein signaling 1 antibody
    • RGS 1 antibody
    • RGS1 antibody
    • RGS1_HUMAN antibody
    see all

Anti-RGS1 antibody 图像


  • Developed using the ECL technique

    Predicted band size : 24 kDa
  • Human Small Intestine (formalin-fixed, paraffin-embedded) stained with ab117077 followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen
  • Human Thymus (formalin-fixed, paraffin-embedded) stained with ab117077 followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-RGS1 antibody (ab117077)参考文献

ab117077 has not yet been referenced specifically in any publications.

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