概述

  • 产品名称Anti-RGR抗体
    参阅全部 RGR 一抗
  • 描述
    兔多克隆抗体to RGR
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide corresponding to a region within the C terminal amino acids region 249-291 (GKSGHLQVPA LIAKMVPTIN AINYALGNEM VCRGIWQCLS PQKREKDRTK) of the Human RGR protein (UniProt: P47804).

  • 阳性对照
    • PANC1 cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab125460 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 32 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 相关性RGR is a putative retinal G-protein coupled receptor and is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. RGR acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal (the reverse isomerization occurs with rhodopsin in retinal photoreceptor cells). RGR is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.
  • 细胞定位Cell Membrane; Multi-pass membrane protein
  • 数据库链接
  • 别名
    • hRGR antibody
    • Ral GDS related protein antibody
    • Retinal G protein coupled receptor antibody
    • RGR-opsin antibody
    • RP44 antibody
    • RPE retinal G protein coupled receptor antibody
    see all

Anti-RGR antibody 图像

  • Anti-RGR antibody (ab125460) at 1 µg/ml + PANC1 cell lysate at 10 µg

    Predicted band size : 32 kDa

Anti-RGR antibody (ab125460)参考文献

ab125460 has not yet been referenced specifically in any publications.

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