概述
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产品名称Anti-RGR抗体
参阅全部 RGR 一抗 -
描述兔多克隆抗体to RGR
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宿主Rabbit
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经测试应用适用于: WBmore details
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种属反应性与反应: Human
预测可用于: Rat, Rabbit, Horse, Chicken, Cow, Cat, Dog, Pig, Zebrafish
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免疫原
Synthetic peptide corresponding to a region within N terminal amino acids 76-125 (
SLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRS
) of Human RGR, isoform 2 (NP_002912). -
阳性对照
- PANC-1 cell lysate
性能
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形式Liquid
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存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
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存储溶液Constituents: 98% PBS, 2% Sucrose
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Concentration information loading... -
纯度Immunogen affinity purified
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克隆多克隆
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同种型IgG
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研究领域
相关产品
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Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab125371 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | Use a concentration of 1 µg/ml. Predicted molecular weight: 32 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T. |
靶标
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相关性RGR is a putative retinal G-protein coupled receptor and is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. RGR acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal (the reverse isomerization occurs with rhodopsin in retinal photoreceptor cells). RGR is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.
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细胞定位Cell Membrane; Multi-pass membrane protein
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数据库链接
- Entrez Gene: 423619 Chicken
- Entrez Gene: 280911 Cow
- Entrez Gene: 489072 Dog
- Entrez Gene: 100065091 Horse
- Entrez Gene: 5995 Human
- Entrez Gene: 100155692 Pig
- Entrez Gene: 100338440 Rabbit
- Entrez Gene: 306307 Rat
see all -
别名
- hRGR antibody
- Ral GDS related protein antibody
- Retinal G protein coupled receptor antibody
see all
图片
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Western blot - Anti-RGR antibody (ab125371)Anti-RGR antibody (ab125371) at 1 µg/ml + PANC-1 cell lysate at 10 µg
Predicted band size: 32 kDa
文献
ab125371 has not yet been referenced specifically in any publications.
客户评价及客户问答
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"