Anti-RFXAP抗体[RFXAD55A] (ab51376)

概述

  • 产品名称Anti-RFXAP抗体[RFXAD55A]
    参阅全部 RFXAP 一抗
  • 描述
    小鼠单克隆抗体[RFXAD55A] to RFXAP
  • 经测试应用适用于: Dot blot, ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to internal sequence amino acids 50-200 of Human RFXAP

  • 阳性对照
    • HeLa whole cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液Preservative: 0.05% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • 纯度Protein G purified
  • 纯化说明Filtered through a 0.22 µm membrane.
  • 克隆单克隆
  • 克隆编号RFXAD55A
  • 同种型IgG1
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab51376 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Dot blot Use at an assay dependent dilution.
ELISA Use at an assay dependent dilution.
WB 1/100. Detects a band of approximately 30 kDa (predicted molecular weight: 28 kDa).

靶标

  • 功能Part of the RFX complex that binds to the X-box of MHC II promoters.
  • 组织特异性Ubiquitous.
  • 疾病相关Defects in RFXAP are a cause of bare lymphocyte syndrome type 2 (BLS2) [MIM:209920]; also known as hereditary MHC class II deficiency or HLA class II-deficient combined immunodeficiency. BLS2 is a severe combined immunodeficiency disease with early onset. It is characterized by a profound defect in constitutive and interferon-gamma induced MHC II expression, absence of cellular and humoral T-cell response to antigen challenge, hypogammaglobulinemia and impaired antibody production. The consequence include extreme susceptibility to viral, bacterial and fungal infections.
  • 翻译后修饰Phosphorylated.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Regulatory factor X associated protein antibody
    • Regulatory factor X-associated protein antibody
    • RFX associated protein antibody
    • RFX DNA binding complex 36 kDa subunit antibody
    • RFX DNA-binding complex 36 kDa subunit antibody
    • RFX-associated protein antibody
    • RFXAP antibody
    • RFXAP_HUMAN antibody
    see all

Anti-RFXAP antibody [RFXAD55A] 图像

  • Anti-RFXAP antibody [RFXAD55A] (ab51376) at 1/100 dilution + HeLa whole cell lysate at 50 µg

    Secondary
    Anti mouse IgG antibody at 1/2500 dilution

    Predicted band size : 28 kDa
    Observed band size : 30 kDa (why is the actual band size different from the predicted?)

Anti-RFXAP antibody [RFXAD55A] (ab51376)参考文献

ab51376 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab51376.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"