概述

  • 产品名称Anti-Rffl抗体
    参阅全部 Rffl 一抗
  • 描述
    小鼠单克隆抗体to Rffl
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: WATCCNWFCL DGQPEEVPPP QGARMQAYSN PGYSSFPSPT GLEPSCKSCG AHFANTARKQ TCLDCKKNFC MTCSSQVGNG PRLCLLCQRF RATAFQRE, corresponding to amino acids 2-100 of Human Rffl

性能

应用

Our Abpromise guarantee covers the use of ab57316 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates.
    • 组织特异性Ubiquitous. Detected in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes.
    • 通路Protein modification; protein ubiquitination.
    • 序列相似性Contains 1 FYVE-type zinc finger.
      Contains 1 RING-type zinc finger.
      Contains 2 SAP domains.
    • 翻译后修饰Rapidly degraded after stimulation with TNFSF10, probably by caspases.
      Auto-ubiquitinated (in vitro).
      Palmitoylated.
    • 细胞定位Cytoplasm. Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CARP-2 antibody
      • CARP2 antibody
      • Caspase regulator CARP2 antibody
      • Caspases 8 and 10 associated RING finger protein 2 antibody
      • caspases-8 and -10- associated RING finger protein 2 antibody
      • Caspases-8 and -10-associated RING finger protein 2 antibody
      • E3 ubiquitin protein ligase rififylin antibody
      • E3 ubiquitin-protein ligase rififylin antibody
      • Fring antibody
      • FYVE RING finger protein Sakura antibody
      • FYVE-RING finger protein Sakura antibody
      • Rffl antibody
      • RFFL_HUMAN antibody
      • Rififylin antibody
      • RING finger and FYVE like domain containing protein antibody
      • RING finger and FYVE-like domain-containing protein 1 antibody
      • RING finger protein 189 antibody
      • RING finger protein 34 like antibody
      • RING finger protein 34-like antibody
      • RNF189 antibody
      • RNF34L antibody
      see all

    Anti-Rffl antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab57316 Rffl antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    Anti-Rffl antibody (ab57316)参考文献

    ab57316 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"