概述

  • 产品名称Anti-Rffl抗体
    参阅全部 Rffl 一抗
  • 描述
    兔多克隆抗体to Rffl
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Human
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 1-50 (MWASCCNWFC LDGQPEEAPP PQGARTQAYS NPGYSSFPSP TGSEPSCKAC) of Mouse Rffl (NP_001158043).

  • 阳性对照
    • Mouse liver lysate.

性能

应用

Our Abpromise guarantee covers the use of ab125344 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 38 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates.
  • 组织特异性Ubiquitous. Detected in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Contains 1 FYVE-type zinc finger.
    Contains 1 RING-type zinc finger.
    Contains 2 SAP domains.
  • 翻译后修饰Rapidly degraded after stimulation with TNFSF10, probably by caspases.
    Auto-ubiquitinated (in vitro).
    Palmitoylated.
  • 细胞定位Cytoplasm. Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CARP-2 antibody
    • CARP2 antibody
    • Caspase regulator CARP2 antibody
    • Caspases 8 and 10 associated RING finger protein 2 antibody
    • caspases-8 and -10- associated RING finger protein 2 antibody
    • Caspases-8 and -10-associated RING finger protein 2 antibody
    • E3 ubiquitin protein ligase rififylin antibody
    • E3 ubiquitin-protein ligase rififylin antibody
    • Fring antibody
    • FYVE RING finger protein Sakura antibody
    • FYVE-RING finger protein Sakura antibody
    • Rffl antibody
    • RFFL_HUMAN antibody
    • Rififylin antibody
    • RING finger and FYVE like domain containing protein antibody
    • RING finger and FYVE-like domain-containing protein 1 antibody
    • RING finger protein 189 antibody
    • RING finger protein 34 like antibody
    • RING finger protein 34-like antibody
    • RNF189 antibody
    • RNF34L antibody
    see all

Anti-Rffl antibody 图像

  • Anti-Rffl antibody (ab125344) at 1 µg/ml + Mouse liver lysate at 10 µg

    Secondary
    Goat anti-Rabbit IgG HRP

    Predicted band size : 38 kDa

Anti-Rffl antibody (ab125344)参考文献

ab125344 has not yet been referenced specifically in any publications.

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