概述

  • 产品名称
    Anti-REXO1抗体
  • 描述
    兔多克隆抗体to REXO1
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide derived from an internal region of Human REXO1.

  • 阳性对照
    • Human brain tissue.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液
    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 50% Glycerol, 49.1% PBS, 0.88% Sodium chloride
    Note: PBS (without Mg2+ and Ca2+)
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    ab111189 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab111189 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 相关性
    REXO1 or Elongin A-binding protein 1 (EloA-BP1) is an exonuclease domain-containing protein that can bind to Elongin. The Elongin complex stimulates the rate of transcription elongation by RNA polymerase II by suppressing the transient pausing of the polymerase at many sites along the DNA template. REXO1 is composed of 1221 amino acids and its mRNA is ubiquitously expressed. EloA-BP1 is capable of binding not only the NH(2)-terminal approximately 120 amino acid region of Elongin A, but also that of SII. Although REXO1 had no detectable effect on the rate of transcription elongation in vitro, it may play some role in the regulation of elongation in vivo.
  • 细胞定位
    Nuclear
  • 数据库链接
  • 别名
    • EloA BP1 antibody
    • ELOABP1 antibody
    • Elongin A binding protein 1 antibody
    • KIAA1138 antibody
    • REX1, RNA exonuclease 1 homolog (S. cerevisiae) antibody
    • RNA exonuclease 1 homolog antibody
    • TCEB3BP1 antibody
    • Transcription elongation factor B polypeptide 3 binding protein 1 antibody
    see all

Anti-REXO1 antibody 图像

  • ab111189 at 1/50 dilution staining REXO1 in paraffin-embedded Human Brain tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide.

Anti-REXO1 antibody (ab111189)参考文献

ab111189 has not yet been referenced specifically in any publications.

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