Anti-Retinoid X Receptor gamma抗体(ab24364)

概述

  • 产品名称Anti-Retinoid X Receptor gamma抗体
    参阅全部 Retinoid X Receptor gamma 一抗
  • 描述
    山羊多克隆抗体to Retinoid X Receptor gamma
  • 特异性This does not cross-react with either RXR alpha or beta.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Pig, Deer
  • 免疫原

    Synthetic peptide:

    RQRSRERAES EAEC

    , corresponding to internal sequence amino acids 113-126 of Human Retinoid X Receptor gamma.

  • 阳性对照
    • Human Brain lysate.

性能

应用

Our Abpromise guarantee covers the use of ab24364 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 0.3 - 2 µg/ml. Detects a band of approximately 48 kDa (predicted molecular weight: 51 kDa). Some bands of unknown identity were also consistently observed around 37 kDa. These bands were successfully blocked by incubation with the immunising peptide.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid.
    • 序列相似性Belongs to the nuclear hormone receptor family. NR2 subfamily.
      Contains 1 nuclear receptor DNA-binding domain.
    • 结构域Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • MGC109416 antibody
      • NR2B3 antibody
      • Nuclear receptor subfamily 2 group B member 3 antibody
      • OTTHUMP00000060418 antibody
      • Retanoic X receptor gamma antibody
      • Retinoic acid receptor RXR gamma antibody
      • Retinoic acid receptor RXR-gamma antibody
      • Retinoid X receptor gamma antibody
      • RXR G antibody
      • RXR gamma antibody
      • RXRC antibody
      • Rxrg antibody
      • RXRG_HUMAN antibody
      • RXRgamma antibody
      see all

    Anti-Retinoid X Receptor gamma antibody 图像

    • Anti-Retinoid X Receptor gamma antibody (ab24364) at 0.3 µg/ml + Human Brain lysate (in RIPA buffer). at 35 µg
      Developed using the ECL technique

      Predicted band size : 51 kDa
      Observed band size : 48 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 37 kDa,90 kDa. We are unsure as to the identity of these extra bands.

      Exposure time : 1 hour

    Anti-Retinoid X Receptor gamma antibody (ab24364)参考文献

    ab24364 has not yet been referenced specifically in any publications.

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