Anti-RXRG抗体(ab15518)
Key features and details
- Rabbit polyclonal to RXRG
- Suitable for: IHC-Fr, ICC/IF, IHC - Wholemount, WB, IHC-P
- Reacts with: Mouse, Rat, Chicken, Hamster, Human
- Isotype: IgG
概述
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产品名称
Anti-RXRG抗体
参阅全部 RXRG 一抗 -
描述
兔多克隆抗体to RXRG -
宿主
Rabbit -
特异性
From Jan 2024, QC testing of replenishment batches of this polyclonal changed. All tested and expected application and reactive species combinations are still covered by our Abcam product promise. However, we no longer test all applications. For more information on a specific batch, please contact our Scientific Support who will be happy to help.
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经测试应用
适用于: IHC-Fr, ICC/IF, IHC - Wholemount, WB, IHC-Pmore details -
种属反应性
与反应: Mouse, Rat, Chicken, Hamster, Human -
免疫原
Synthetic peptide within Mouse RXRG aa 1-100 (N terminal). The exact sequence is proprietary.
Database link: P28705 -
常规说明
This product is FOR RESEARCH USE ONLY. For commercial use, please contact partnerships@abcam.com.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.60
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab15518于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-Fr | (1) |
Use at an assay dependent concentration.
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ICC/IF | (2) |
Use at an assay dependent concentration.
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IHC - Wholemount | (1) |
Use at an assay dependent concentration.
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WB | (2) |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 51 kDa.
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IHC-P | (4) |
1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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说明 |
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IHC-Fr
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. |
IHC - Wholemount
Use at an assay dependent concentration. |
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 51 kDa. |
IHC-P
1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
靶标
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功能
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. -
序列相似性
Belongs to the nuclear hormone receptor family. NR2 subfamily.
Contains 1 nuclear receptor DNA-binding domain. -
结构域
Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 396231 Chicken
- Entrez Gene: 6258 Human
- Entrez Gene: 20183 Mouse
- Entrez Gene: 83574 Rat
- Omim: 180247 Human
- SwissProt: P28701 Chicken
- SwissProt: P48443 Human
- SwissProt: P28705 Mouse
see all -
别名
- MGC109416 antibody
- NR2B3 antibody
- Nuclear receptor subfamily 2 group B member 3 antibody
see all
图片
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Anti-RXRG antibody (ab15518) at 1/25 dilution + NIH3T3 cell lysate
Predicted band size: 51 kDa
Observed band size: 55 kDa why is the actual band size different from the predicted? -
ab15518 staining RXRG in breast carcinoma by Immunohistochemistry (FFPE-sections).
数据表及文件
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SDS download
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Datasheet download
文献 (15)
ab15518 被引用在 15 文献中.
- Gao K et al. Qishen granules exerts cardioprotective effects on rats with heart failure via regulating fatty acid and glucose metabolism. Chin Med 15:21 (2020). PubMed: 32158496
- Thulasi Raman SN et al. Dysregulation of Ephrin receptor and PPAR signaling pathways in neural progenitor cells infected by Zika virus. Emerg Microbes Infect 9:2046-2060 (2020). PubMed: 32873194
- Wang GS et al. Expression and localization of retinoid receptors in the testis of normal and infertile men. Mol Reprod Dev 87:978-985 (2020). PubMed: 32770619
- Joseph C et al. Retinoid X receptor gamma (RXRG) is an independent prognostic biomarker in ER-positive invasive breast cancer. Br J Cancer 121:776-785 (2019). PubMed: 31558802
- Aldunate EZ et al. Conditional Dicer1 depletion using Chrnb4-Cre leads to cone cell death and impaired photopic vision. Sci Rep 9:2314 (2019). PubMed: 30783126