Anti-Retinoid X Receptor beta抗体- ChIP Grade (ab5793)

概述

  • 产品名称Anti-Retinoid X Receptor beta抗体- ChIP Grade
    参阅全部 Retinoid X Receptor beta 一抗
  • 描述
    兔多克隆抗体to Retinoid X Receptor beta - ChIP Grade
  • 经测试应用适用于: ChIP, IHC - Wholemount, IP, WBmore details
  • 种属反应性
    与反应: Mouse, Cow, Human
    预测可用于: Rat, Dog
  • 免疫原

    Synthetic peptide corresponding to Mouse Retinoid X Receptor beta aa 190-202.
    Sequence:

    QKSDQGVEGPGAT

性能

应用

Our Abpromise guarantee covers the use of ab5793 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ChIP Use at an assay dependent concentration.
IHC - Wholemount Use at an assay dependent concentration.
IP Use at an assay dependent concentration.
WB 1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 63 kDa).

Detects a band of approximately 50 kDa representing RXR beta from COS cells transfected with the human gene (predicted molecular weight: 63 kDa).

EMSA Use at an assay dependent concentration.

Gel shift assays reveal supershifting of vitamin D receptor (VDR)/RXR beta/vitamin D receptor response element (VDRE) complexes when ab5739 is preincubated with RXR beta prior to addition of VDR.

靶标

  • 相关性Retinoid X receptors (RXRs) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. The RXR subfamily consists of at least three similar genes, RXR alpha, RXR beta and RXR gamma, all of which control transcription of target genes mediated by retinoids. RXR beta controls expression of many genes that respond to hormones and vitamins, including thyroid hormone, estrogen, retinoids and vitamin D. RXR beta controls a wide array of genes because of its ability to heterodimerize with other hormone receptors including the thyroid hormone receptor (THR), vitamin D receptor (VDR) and retinoic acid receptor (RAR).
  • 细胞定位Nuclear
  • 数据库链接
  • 别名
    • DAUD I6 antibody
    • DAUDI6 antibody
    • H 2RIIBP antibody
    • H2RIIBP antibody
    • MGC1831 antibody
    • MHC class I promoter binding protein antibody
    • NR2B2 antibody
    • nuclear receptor subfamily 2 group B member 2 antibody
    • RCoR 1 antibody
    • RCoR1 antibody
    • Retinoic acid receptor RXR beta antibody
    • RXR beta antibody
    • RXRB antibody
    • RXRbeta antibody
    see all

Anti-Retinoid X Receptor beta antibody - ChIP Grade 图像

  • Anti-Retinoid X Receptor beta antibody - ChIP Grade (ab5793) at 1/1000 dilution + Recombinant Human Retinoid X Receptor beta protein (ab82122) at 0.1 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution

    Exposure time : 3 minutes

Anti-Retinoid X Receptor beta antibody - ChIP Grade (ab5793)参考文献

ab5793 has not yet been referenced specifically in any publications.

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