Anti-Retinoid X Receptor beta抗体(ab23939)

概述

  • 产品名称Anti-Retinoid X Receptor beta抗体
    参阅全部 Retinoid X Receptor beta 一抗
  • 描述
    山羊多克隆抗体to Retinoid X Receptor beta
  • 特异性Does not cross react with either RXR alpha or gamma.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Dog, Pig
  • 免疫原

    Synthetic peptide:

    (C)RDGMGDSGRDSRSP

    , corresponding to amino acids 70 - 83 of Human Retinoid X Receptor beta.

  • 阳性对照
    • Lysate prepared from A431 cells. Lysate prepared from transfected HEK293 cells transiently expressing Retinoid X Receptor beta.

性能

应用

Our Abpromise guarantee covers the use of ab23939 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 59 kDa).

靶标

  • 相关性Retinoid X receptors (RXRs) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. The RXR subfamily consists of at least three similar genes, RXR alpha, RXR beta and RXR gamma, all of which control transcription of target genes mediated by retinoids. RXR beta controls expression of many genes that respond to hormones and vitamins, including thyroid hormone, estrogen, retinoids and vitamin D. RXR beta controls a wide array of genes because of its ability to heterodimerize with other hormone receptors including the thyroid hormone receptor (THR), vitamin D receptor (VDR) and retinoic acid receptor (RAR).
  • 细胞定位Nuclear
  • 数据库链接
  • 别名
    • DAUD I6 antibody
    • DAUDI6 antibody
    • H 2RIIBP antibody
    • H2RIIBP antibody
    • MGC1831 antibody
    • MHC class I promoter binding protein antibody
    • NR2B2 antibody
    • nuclear receptor subfamily 2 group B member 2 antibody
    • RCoR 1 antibody
    • RCoR1 antibody
    • Retinoic acid receptor RXR beta antibody
    • RXR beta antibody
    • RXRB antibody
    • RXRbeta antibody
    see all

Anti-Retinoid X Receptor beta antibody 图像

  • Anti-Retinoid X Receptor beta antibody (ab23939) at 1 µg/ml + A431 lysate (RIPA buffer) at 35 µg

    Predicted band size : 59 kDa
  • Anti-Retinoid X Receptor beta antibody (ab23939) at 3 µg/ml + lysate prepared from transfected HEK293 cells transiently expressing Retinoid X Receptor beta

    Predicted band size : 59 kDa
    Observed band size : 62 kDa (why is the actual band size different from the predicted?)

Anti-Retinoid X Receptor beta antibody (ab23939)参考文献

ab23939 has not yet been referenced specifically in any publications.

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