Anti-Retinoic Acid Receptor gamma抗体[H5620] (ab41938)

概述

  • 产品名称Anti-Retinoic Acid Receptor gamma抗体[H5620]
    参阅全部 Retinoic Acid Receptor gamma 一抗
  • 描述
    小鼠单克隆抗体[H5620] to Retinoic Acid Receptor gamma
  • 特异性This antibody specifically recognizes RAR gamma but does not recognize RAR alpha and beta.
  • 经测试应用适用于: ELISA, WB, IPmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Baculovirus-expressed recombinant fragment: ATNKERLFAA GALGPGSGYP GAGFPFAFPG ALRGSPPFEM LSPSFRGLGQ PDLPKEMASL SVETQSTSSE EMVPSSPSPP PPPRVYK, corresponding to N terminal amino acids 2/88 of Human Retinoic Acid Receptor gamma

性能

应用

Our Abpromise guarantee covers the use of ab41938 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
IP
  • 应用说明ELISA: Use at a concentration of 0.06 µg/ml (A450 = 0.5).
    IP: Use at an assay dependent dilution.
    WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: 50 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function.
    • 序列相似性Belongs to the nuclear hormone receptor family. NR1 subfamily.
      Contains 1 nuclear receptor DNA-binding domain.
    • 结构域Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • NR1B3 antibody
      • Nuclear receptor subfamily 1 group B member 3 antibody
      • RAR gamma antibody
      • RAR-gamma antibody
      • RARC antibody
      • Rarg antibody
      • RARG_HUMAN antibody
      • Retinoic acid receptor gamma 2 antibody
      • Retinoic acid receptor gamma antibody
      • Retinoic acid receptor, gamma antibody
      see all

    Anti-Retinoic Acid Receptor gamma antibody [H5620] (ab41938)参考文献

    ab41938 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for taking time to contact us. I am sorry to hear that this antibody is not providing satisfactory results.

    From the WB image sent, it does look like you're getting a strong specific band at 50 kDa, which is the predicted MW for RA...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"