Anti-Retinoic Acid Receptor gamma 2抗体(ab5905)

概述

  • 产品名称Anti-Retinoic Acid Receptor gamma 2抗体
    参阅全部 Retinoic Acid Receptor gamma 2 一抗
  • 描述
    兔多克隆抗体to Retinoic Acid Receptor gamma 2
  • 特异性This antibody does not detect RAR gamma-1, or either of the alpha or beta forms of RAR.
  • 经测试应用适用于: IP, IHC-P, WBmore details
  • 种属反应性
    与反应: Human, Non Human Primates
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide corresponding to Human Retinoic Acid Receptor gamma 2 aa 13-28 (N terminal).
    Sequence:

    RRLYGAAGPGAGLLRR


    (Peptide available as ab39774)

性能

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应用

Our Abpromise guarantee covers the use of ab5905 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.
WB 1/500 - 1/5000. Predicted molecular weight: 50 kDa.Can be blocked with Human Retinoic Acid Receptor gamma 2 peptide (ab39774).
EMSA Use 1µl for 102 cells.

靶标

  • 功能Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function.
  • 序列相似性Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • 结构域Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • NR1B3 antibody
    • Nuclear receptor subfamily 1 group B member 3 antibody
    • RAR gamma antibody
    • RAR gamma isoform 2 antibody
    • RAR gamma2 antibody
    • RAR-gamma antibody
    • RARC antibody
    • Rarg antibody
    • RARG_HUMAN antibody
    • retinoic acid nuclear receptor gamma variant 1 antibody
    • retinoic acid nuclear receptor gamma variant 2 antibody
    • Retinoic acid receptor gamma antibody
    see all

Anti-Retinoic Acid Receptor gamma 2 antibody 图像

  • All lanes : Anti-Retinoic Acid Receptor gamma 2 antibody (ab5905) at 1/1000 dilution

    Lane 1 : SK-BR-3 cell lysate
    Lane 2 : HeLa cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 50 kDa
    Observed band size : 50 kDa

Anti-Retinoic Acid Receptor gamma 2 antibody (ab5905)参考文献

ab5905 has not yet been referenced specifically in any publications.

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