Anti-Retinoic Acid Receptor gamma 1抗体(ab5904)

概述

  • 产品名称
    Anti-Retinoic Acid Receptor gamma 1抗体
  • 描述
    兔多克隆抗体to Retinoic Acid Receptor gamma 1
  • 经测试应用
    适用于: IP, WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rabbit
  • 免疫原

    Synthetic peptide corresponding to Retinoic Acid Receptor gamma 1 aa 40-57 (N terminal).
    Sequence:

    EMLSPSFRGLGQPDLPKE


    (Peptide available as ab39773)

性能

应用

Our Abpromise guarantee covers the use of ab5904 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP Use at an assay dependent concentration.
WB 1/2000. Detects a band of approximately 50 kDa (predicted molecular weight: 54 kDa).Can be blocked with Human Retinoic Acid Receptor gamma 1 peptide (ab39773).
IHC-P Use at an assay dependent concentration.
EMSA Use 1µl for 102 cells.

Use 1-2µl. ab5904 has been shown to efficiently super shift the human RAR gamma-1/retinoid X receptor (RXR)/RAR response element complex in gel super shift experiments using a number of different response elements.

靶标

  • 功能
    Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function.
  • 序列相似性
    Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • 结构域
    Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
  • 细胞定位
    Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • NR1B3 antibody
    • Nuclear receptor subfamily 1 group B member 3 antibody
    • RAR gamma antibody
    • RAR gamma isoform 1 antibody
    • RAR-gamma antibody
    • RARC antibody
    • Rarg antibody
    • RARG_HUMAN antibody
    • Retinoic acid receptor gamma antibody
    see all

Anti-Retinoic Acid Receptor gamma 1 antibody 图像

  • All lanes : Anti-Retinoic Acid Receptor gamma 1 antibody (ab5904)

    Lane 1 : HEK293 cell lysate with neutralizing peptide
    Lane 2 : HEK293 cell lysate


    Predicted band size : 54 kDa

Anti-Retinoic Acid Receptor gamma 1 antibody (ab5904)参考文献

This product has been referenced in:
  • Joss-Moore L  et al. Intrauterine growth restriction transiently delays alveolar formation and disrupts retinoic acid receptor expression in the lung of female rat pups. Pediatr Res 73:612-20 (2013). Read more (PubMed: 23419538) »

See 1 Publication for this product

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I can confirm that ab5904 Retinoic Acid Receptor gamma 1 antibody is sold as whole antiserum.

Unpurified antibodies, such as those sold as whole antiserum, ascites or tissue culture supernatant will not ...

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