Anti-Retinoic Acid Receptor beta抗体, prediluted (ab15516)

概述

  • 产品名称Anti-Retinoic Acid Receptor beta抗体, prediluted
    参阅全部 Retinoic Acid Receptor beta 一抗
  • 描述
    兔多克隆抗体to Retinoic Acid Receptor beta, prediluted
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (N terminal).

  • 阳性对照
    • Testis and heart.

性能

应用

Our Abpromise guarantee covers the use of ab15516 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: Ready to use for 10 min at room temperature.
    Staining of formalin fixed tissues requires boiling tissue sections in 10mM
    citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.
    • 疾病相关Microphthalmia, syndromic, 12
    • 序列相似性Belongs to the nuclear hormone receptor family. NR1 subfamily.
      Contains 1 nuclear receptor DNA-binding domain.
    • 结构域Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
    • 细胞定位Cytoplasm and Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • HAP antibody
      • HBV-activated protein antibody
      • NR1B2 antibody
      • Nuclear receptor subfamily 1 group B member 2 antibody
      • RAR B antibody
      • RAR beta antibody
      • RAR epsilon antibody
      • RAR-beta antibody
      • RAR-epsilon antibody
      • RARB antibody
      • RARB_HUMAN antibody
      • Retinoic acid receptor beta 2 antibody
      • Retinoic acid receptor beta 4 antibody
      • Retinoic acid receptor beta 5 antibody
      • Retinoic acid receptor beta antibody
      • Retinoic acid receptor beta polypeptide antibody
      • RRB2 antibody
      see all

    Anti-Retinoic Acid Receptor beta antibody, prediluted 图像

    •  ab15516 staining Retinoic Acid Receptor Beta in human testis by Immunohistology (formalin/paraffin).

    Anti-Retinoic Acid Receptor beta antibody, prediluted (ab15516)参考文献

    ab15516 has not yet been referenced specifically in any publications.

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