The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
应用说明AP (immunopurification of arrestin): Use at an assay dependent dilution.
ICC/IF: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
功能Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase.
组织特异性Retina and pineal gland.
疾病相关Defects in SAG are a cause of congenital stationary night blindness Oguchi type 1 (CSNBO1) [MIM:258100]; also known as Oguchi disease. Congenital stationary night blindness is a non-progressive retinal disorder characterized by impaired night vision. CSNBO is an autosomal recessive form associated with fundus discoloration and abnormally slow dark adaptation.
S antigen retina and pineal gland (arrestin) antibody
S arrestin antibody
Anti-Retinal S antigen antibody [PDS-1] 图像
Immunocytochemistry - Retinal S antigen antibody [PDS-1] (ab48360)This image is courtesy of an Anonymous Abreview.
ab43860 staining Retinal S antigen in cultured WERI-RB27 Human Retinoblastoma Cells by Immunocytochemistry. Cells were fixed in cytospin solution and permeabilized in Tween-PBS prior to blocking in 2.5% serum for 15 minutes at 21°C. The primary antibody was diluted 1/200 in PBS and incubated with the sample for 1 hour at 21°C. The secondary antibody was Biotin-conjugated Goat anti-Mouse polyclonal.