Anti-Respiratory Syncytial Virus G Glycoprotein抗体[RSV133] (ab94966)

概述

  • 产品名称Anti-Respiratory Syncytial Virus G Glycoprotein抗体[RSV133]
  • 描述
    小鼠单克隆抗体[RSV133] to Respiratory Syncytial Virus G Glycoprotein
  • 经测试应用适用于: ELISA, WB, ICC/IF, IHC-Frmore details
  • 种属反应性
    与反应: Other
  • 免疫原

    Human Respiratory Syncytial Virus strain A2 infected HeLa cells

  • 常规说明Fusion partner: PS-NS/1-Ag4


    ab94966 is useful for the identification and location of expression of the G glycoprotein of Human Respiratory Syncytial Virus (HRSV) of both sub-groups A and B . This antibody confers passive protection against HRSV of both subgroups in an animal model of hRSV infection.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 纯度Protein A purified
  • Primary antibody说明ab94966 is useful for the identification and location of expression of the G glycoprotein of Human Respiratory Syncytial Virus (HRSV) of both sub-groups A and B . This antibody confers passive protection against HRSV of both subgroups in an animal model of hRSV infection.
  • 克隆单克隆
  • 克隆编号RSV133
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab94966 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 33 kDa.
ICC/IF Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration. Fix with Acetone.

靶标

  • 相关性Respiratory Syncytial Virus (RSV) G Glycoprotein attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. It interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, it lacks both neuraminidase and hemagglutinating activities.
  • 细胞定位Virion membrane. Host cell surface
  • 别名
    • Attachment glycoprotein G antibody
    • G antibody
    • Major surface glycoprotein G antibody
    • Membrane bound glycoprotein antibody
    • mG antibody
    • RSV G Glycoprotein antibody
    see all

Anti-Respiratory Syncytial Virus G Glycoprotein antibody [RSV133] (ab94966)参考文献

This product has been referenced in:
  • Le Nouën C  et al. Attenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization. Proc Natl Acad Sci U S A 111:13169-74 (2014). Read more (PubMed: 25157129) »

See 1 Publication for this product

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I was trying to find the source of the statement: "This antibody confers passive protection against HRSV of both subgroups in an animal model of hRSV infec...

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We used Human RSV strain A2 infected HeLa cells to raise this antibody. The exact epitope sequence has not been determined so I am sorry we do not have, any extra information, other than what is already on the datashee...

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