All tags NF-kB p65 post-translational modifications

p65 post-translational modifications

Explore post-translational modifications and their roles in p65 activation.

Post-translational  modifications, including acetylation, phosphorylation, and methylation, determine the activation status of p65 . Find out where these modifications occur and whether they enhance or repress p65 transcriptional activity using the diagram below.

Figure 1. p65 post translational modifications. The locations of post-translational modifications are shown, along with the effect they have on p65 transcriptional activity. Click to expand image.

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ModificationAmino acidRecommended antibodies
PhosphorylationT254ab131100
S281ab193238
S311ab194926
T435ab194932,  ab31472
S468ab194921
S529ab109458, ab47395
S536ab86299,  ab76302
AcetylationK310ab19870