概述

  • 产品名称Anti-RERE抗体
    参阅全部 RERE 一抗
  • 描述
    兔多克隆抗体to RERE
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Saccharomyces cerevisiae, Drosophila melanogaster
  • 免疫原

    Synthetic peptide corresponding to a region within the N terminal amino acids 1-50 (TADKDKDKDKEKDRDRDRDREREKRDKARESENSRPRRSCTLEGGAKNY A) of Human RERE, NP_036234

  • 阳性对照
    • 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab86231 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 172 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.
  • 组织特异性Widely expressed. Expressed in tumor cell lines.
  • 疾病相关Note=A chromosomal aberration involving RERE is found in the neuroblastoma cell line. Translocation t(1;15)(p36.2;q24).
  • 序列相似性Contains 1 BAH domain.
    Contains 1 ELM2 domain.
    Contains 1 GATA-type zinc finger.
    Contains 1 SANT domain.
  • 结构域The interaction with ATN1 is mediated by the coiled coil domain.
  • 细胞定位Nucleus. Localized in nuclear bodies of variables size. Colocalized with PML and BAX in nuclear PODs.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 1110033A15Rik antibody
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    • arginine glutamic acid dipeptide (RE) repeats antibody
    • arginine glutamic acid dipeptide repeats antibody
    • Arginine glutamic acid dipeptide repeats protein antibody
    • Arginine-glutamic acid dipeptide repeats protein antibody
    • ARGININE-GLUTAMIC ACID REPEATS-ENCODING GENE antibody
    • ARP antibody
    • ATN1L antibody
    • Atr2 antibody
    • atrophin 1 like antibody
    • Atrophin 1 like protein antibody
    • Atrophin 1 related protein antibody
    • atrophin 2 antibody
    • atrophin related protein antibody
    • ATROPHIN-1-ASSOCIATED PROTEIN antibody
    • Atrophin-1-like protein antibody
    • Atrophin-1-related protein antibody
    • atrophin-2 antibody
    • ATROPHIN-RELATED PROTEIN antibody
    • AW742570 antibody
    • DNB1 antibody
    • FLJ38775 antibody
    • KIAA0458 antibody
    • mKIAA0458 antibody
    • OTTHUMP00000001701 antibody
    • Rere antibody
    • RERE_HUMAN antibody
    see all

Anti-RERE antibody 图像

  • Anti-RERE antibody (ab86231) at 1 µg/ml + 293T cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 172 kDa

Anti-RERE antibody (ab86231)参考文献

ab86231 has not yet been referenced specifically in any publications.

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